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The Lasting Impact of Early-life Adversity on Individuals and Their Descendants: Potential Mechanisms and Hope for Intervention

Early life stress profoundly impacts mental health across a lifespan. Studies, particularly with animals, show it alters brain development, fear learning, and stress responses, increasing the risk of psychopathology.

StressEpigeneticsLearningMemoryTreatmentChildrenEarly-life stressemotion regulationfear learning
(2016)

The Role of Social Determinants in Explaining Racial/Ethnic Disparities in Perinatal Outcomes

The US has significant racial/ethnic disparities in infant mortality, driven by higher preterm birth rates among minority women. Social determinants of health, like income, education, housing, and racism, mediate these differences.

PregnancyEnvironmentRaceEthnicity
(2016)

When Is an Adolescent an Adult? Assessing Cognitive Control in Emotional and Nonemotional Contexts

Legal definitions of adulthood vary, but brain development, especially in areas controlling behavior, continues into the early 20s. This suggests that cognitive control in emotional situations may mature later than in neutral ones.

AdolescenceSelf-controlEmotionsfMRILegal policyBrain developmentyoung adultdevelopmentcognitive control
(2016)

Young Adulthood as a Transitional Legal Category: Science, Social Change, and Justice Policy

The article finds that developmental brain research suggests young adults, like juveniles, are less culpable for crimes and have a greater potential for reform. This research supports reconsidering how the law treats offenders up to age 21.

young adult offenderscrime reductiondevelopmental researcheffective sentencingsocial welfare
(2016)

Brief for Amici Curiae The Legal Action Center, et al., in Support of Appellants

Amici argue that New York law protects people with conviction histories from hiring discrimination by both direct employers and controlling third parties. They assert that entities dictating "no-hire" policies are liable.

discriminationconviction historiesindividualized assessments
(2016)

Adolescents in Peer Groups Make More Prudent Decisions When a Slightly Older Adult Is Present

Adolescents take more risks in groups than alone, but having an older adult present may reduce this behavior. This study examined how an adult's presence affects group decision-making and risk-taking among late adolescents.

Brain developmentRisk takingDecision makingPeer influenceAdult figureAdolescent developmentjudgmentintergroup dynamics
(2016)

Alcohol and Drug Use and the Developing Brain

Adolescent substance use, especially alcohol and marijuana, begins earlier in life and correlates with poorer outcomes. This review focuses on how substance use impacts crucial brain development during this period.

AlcoholMarijuanaSubstance useYouthMental developmentBrain scansBrain functioningTestingControlDevelopmentNeural developmentCognitive functioningNeuropsychological testingMagnetic resonance imaging (MRI)Functional MRI (fMRI)
(2016)

An Upside to Reward Sensitivity: the Hippocampus Supports Enhanced Reinforcement Learning in Adolescence

Adolescents learn better from positive and negative feedback than adults. This enhanced learning is linked to greater activity in brain regions associated with memory and reward processing.

YouthReward-seekingBrain activityBrain scanMemoryLearning
(2016)

Buffering Social Influence: Neural Correlates of Response Inhibition Predict Driving Safety in the Presence of a Peer

Social influence impacts behavior throughout life, especially among adolescent peers. Susceptibility to influence can lead to risky behaviors like drug or alcohol use and unsafe driving.

DrivingTeenagers Risk taking Control Brain scans Safer choices
(2016)

Frontostriatal White Matter Integrity Predicts Development of Delay of Gratification: a Longitudinal Study

This study found that the ability to delay gratification improves with age. Maturation of brain connections between reward and control centers predicts this improvement.

TeenagersBrain developmentWhite matterImpulsivitySelf-controladolescencedevelopmentimpulsivitylongitudinal
(2016)

Neurobiology of Addiction: a Neurocircuitry Analysis

Drug addiction is a chronic, relapsing disorder with a cycle of binge/intoxication, withdrawal, and craving. This condition involves neuroplastic changes in the brain's reward, stress, and executive function systems.

Drug useDecision makingNeuroscience
(2016)

Peer Passenger Norms and Pressure: Experimental Effects on Simulated Driving Among Teenage Males

Teen crash rates are higher than adults due to inexperience and development. Peers, especially male passengers, increase risk-taking in adolescent drivers.

Risk takingTeenagersDrivingPeer influenceTeen DriverRisky DrivingBehaviorSimulated DrivingHazard PerceptionSocial InfluencesInjunctive Norms
(2016)

Searching for Signatures of Brain Maturity: What Are We Searching For?

Neuroscientific evidence of brain development is increasingly used in legal and policy discussions. However, there is no scientific consensus on what constitutes a "mature" brain, as development continues past age 30.

youthadolescencebrain developmentneurosciencejuvenile justiceneurodevelopmentdevelopmentmaturitybrain imagingadolescencepolicy
(2016)

The Dual Systems Model: Review, Reappraisal, and Reaffirmation

Adolescent risk-taking is linked to different brain systems developing at different rates. A system seeking rewards matures earlier than the system controlling impulses, contributing to risky behaviors during these years.

AdolescentsRisk takingRewardsControlBrain developmentDual systemsSensation-seekingReward sensitivityCognitive control
(2016)

The Neurobiology of the Emotional Adolescent: From the Inside Out

Adolescent emotional lives are complex, shaped by hormonal changes, brain development, and evolving social relationships. Research shows three main connections between neurobiology and emotions in adolescence.

AffectBrainfMRIPubertyphysiologyindividual differencessocial context
(2016)