Resource Library
New to the Resource Library?
Learn how to navigate, search, and use our resources effectively.
Reward neurocircuitry predicts longitudinal changes in alcohol use following trauma exposure
This study explored how brain responses to reward in recently traumatized individuals predict changes in alcohol use. It also examined how these brain differences might vary between sexes.
Common neural patterns of substance use disorder: A seed-based resting-state functional connectivity meta-analysis
Substance use disorder (SUD) involves complex brain changes. Research identifies consistent functional connectivity abnormalities in brain reward circuits across different substances and addiction stages, linking these to impulsivity.
Prevalence of adverse childhood experiences among individuals in treatment for substance use disorder: Are ACE associated differently across type of abuse and quantity of consumption?
Adverse Childhood Experiences (ACE) are linked to many adult health issues. Studies find Indigenous populations, including those in Greenland, experience more ACE and are more likely to develop substance use disorders.
Recovery housing for substance use disorder: A systematic review
Substance use disorder (SUD) is a major global public health problem. Recovery housing offers vital long-term support, significantly improving recovery outcomes and cost-effectiveness for those seeking remission.
Redefining low-threshold buprenorphine access in an integrated mobile clinic program: Factors associated with treatment retention
A mobile clinic in Baltimore City expanded its low-barrier buprenorphine program by increasing time between visits and drug testing. These changes aimed to further reduce barriers to care for people who use drugs or experience homelessness.
Unravelling Polygenic risk and Environmental Interactions in Adolescent Polysubstance Use: a US Population-Based Observational Study
This study explores how genetic risks and environmental factors interact to influence adolescent polysubstance use. Findings aim to reveal underlying mechanisms and inform prevention strategies for substance use disorders.
Drug Addiction and Incarceration: A Call for Research and Transparency Among Prison-Based Substance Abuse Treatment programs
A significant majority of incarcerated individuals in the U.S. have a history of illicit drug use, and over half have diagnosable addictions. This highlights an urgent need for effective, transparent prison-based treatment programs.
Recruitment of Neuronal Populations in the Paraventricular Thalamus of Alcohol-Seeking Rats With Withdrawal-Related Learning Experience
The study identified neurons activated by environmental cues linked to alcohol in rats, showing different brain activity in dependent versus nondependent animals.
Alternative splicing in addiction
Addiction is a chronic disease marked by compulsive drug or alcohol use despite harmful outcomes, affecting many adults. Drugs of abuse all hijack the brain's reward circuit to increase dopamine, causing reinforcing effects.
Peripheral molecular and brain structural profile implicated stress activation and hyperoxidation in methamphetamine use disorder
This study investigated changes in blood molecules in people with methamphetamine use disorder. It found links between these molecular changes and brain structure alterations, potentially offering insights for treatment.
U.S. substance use harm reduction efforts: A review of the current state of policy, policy barriers, and recommendations
Substance use disorders and overdose deaths are rising, significantly impacting the U.S. Fentanyl drives many overdoses, but other drug-related harms and infectious diseases are also increasing.
Inequities in Opioid Administration by Race and Ethnicity for Hospitalized Patients With and Without Substance Use Disorders
Minority patients with substance use disorders received fewer daily opioid doses for pain management during hospitalization. This disparity remained even after accounting for various clinical and demographic factors.
Helping Opioid Use Disorder and PTSD with Exposure (HOPE): An Open-Label Pilot Study of a Trauma-Focused, Integrated Therapy for OUD/PTSD
Opioid use disorder and posttraumatic stress disorder often occur together, making treatment complex. New integrated psychotherapies are needed for individuals with both conditions to improve treatment outcomes.
Exploring Social Impairment in Those With Opioid Use Disorder: Linking Impulsivity, Childhood Trauma, and the Prefrontal Cortex
Opioid use disorder is a major public health issue, with nearly 80% of drug-related deaths linked to opioids. Impulsivity and childhood adversity are risk factors that can impact treatment and recovery.
Promising Opportunities to Intervene on Adolescent Substance Use
Drug overdose deaths and non-medical prescription drug use have declined among adolescents. Illicit drug, cannabis, alcohol, and nicotine vaping also decreased, though adolescent substance use disorder remains a concern.