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Addiction III: From mouse to man
Substance use disorder and addiction are growing problems with inadequate treatment options. Further research is needed to understand vulnerability, how substances affect vulnerability, and to develop novel treatments.
Modeling as Visioning: Exploring the Impact of Criminal Justice Reform on Health of Populations with Substance Use Disorders
The overdose crisis highlights the failure of criminal-legal drug responses. This calls for exploring alternative policies through simulation modeling to understand their potential health and economic impacts.
Factors associated with problematic substance use before and during the COVID-19 pandemic among a drug addiction recovery cohort: A prospective study in the Netherlands, Belgium, and UK
The COVID-19 pandemic did not increase problematic substance use in a recovery group. Internal commitment was more crucial for preventing relapse during the pandemic, highlighting the importance of personal recovery resources.
Emotion regulation in substance use disorders: a systematic review and meta-analysis
Individuals with substance use disorders (SUDs) consistently report greater difficulties with emotion regulation than those without SUDs. This difficulty may represent a key target for SUD treatment.
Transcriptional signatures of heroin intake and relapse throughout the brain reward circuitry in male mice
This study used a mouse model to identify how opioid use changes gene expression in the brain. Researchers found these changes support long-term opioid use and relapse, mirroring human opioid use disorder.
Opioids and opioid receptors; understanding pharmacological mechanisms as a key to therapeutic advances and mitigation of the misuse crisis
Opioids, while effective for pain management, cause significant adverse effects like respiratory depression and addiction.
The Necessity of a Trauma-Informed Paradigm in Substance Use Disorder Services
Early childhood trauma profoundly alters brain development, increasing the risk of substance use disorders later in life. These changes affect emotion regulation and how individuals respond to rewards.
Collateral consequences of the school-to-prison pipeline: Adolescent substance use and developmental risk
Exclusionary school discipline, like suspensions, may increase substance use and reduce social support among adolescents. This type of discipline is a potential cause of substance use and developmental risks.
Substance use disorders among adults during imprisonment in a medium security prison: Prevalence and risk indicators
This study examines the prevalence of substance use disorders among prisoners in Ghana's only medium-security prison. It investigates factors associated with these disorders, including alcohol use and other psychiatric conditions.
Identifying and Treating Incarcerated Women Experiencing Substance Use Disorders: A Review
Incarcerated women in the US have higher rates of substance use disorder than men, often linked to past trauma and violence. Treatment needs to address these unique pathways and consider factors like parenting status.
Medications for opioid use disorder during incarceration and post-release outcomes
Providing medication for opioid use disorder to incarcerated people increases their engagement in community treatment and lowers post-release overdose risk.
Quality of Opioid Use Disorder Treatment for Persons With and Without Disabling Conditions
Adults with disabilities and opioid use disorder are less likely to start and continue medication for opioid use disorder than those without disabilities. People with disabilities face more barriers to treatment.
[Proposed] Brief Amici Curiae in Support of Appellant, O.R., by Amici Drug Policy Alliance, Any Positive Change, the Beyond Do No Harm Network, et al.
This brief argues that a child was wrongly removed from a father based on a single drug test, without evidence of harm. It challenges the legal assumption that drug use automatically creates a substantial risk to children.
Association Between Stimulant Treatment and Substance Use Through Adolescence Into Early Adulthood
Stimulant medication for childhood ADHD did not increase or decrease risk for substance use or substance use disorder in adulthood. This finding holds true even after considering age and other factors.
Prevalence of Attention Deficit Hyperactivity Disorder (ADHD) among Substance Use Disorder (SUD) Populations: Meta-Analysis
A new meta-analysis found a high prevalence of ADHD in adults with substance use disorder (SUD). This highlights the need for routine ADHD screening for SUD patients, which could improve treatment strategies.