Quality of Opioid Use Disorder Treatment for Persons With and Without Disabling Conditions
Cindy Thomas
Maureen Steward
Emily Ledingham
SimpleOriginal

Summary

People with disabilities are less likely to receive or continue MOUD than those without disabilities. Addressing stigma, improving access, and enforcing disability rights are key to making OUD care more equitable.

2023

Quality of Opioid Use Disorder Treatment for Persons With and Without Disabling Conditions

Keywords substance use; methadone; opioid; opioid use; disability

Abstract

Importance: Adverse outcomes associated with opioid use disorder (OUD) are disproportionately high among people with disabilities (PWD) compared with those without disability. A gap remains in understanding the quality of OUD treatment for people with physical, sensory, cognitive, and developmental disabilities, specifically regarding medications for OUD (MOUD), a foundation of treatment. Objective: To examine the use and quality of OUD treatment in adults with diagnosed disabling conditions, compared with adults without these diagnoses. Design, Setting, and Participants: This case-control study used Washington State Medicaid data from 2016 to 2019 (for use) and 2017 to 2018 (for continuity). Data were obtained for outpatient, residential, and inpatient settings with Medicaid claims. Participants included Washington State full-benefit Medicaid enrollees aged 18 to 64 years, continuously eligible for 12 months, with OUD during the study years and not enrolled in Medicare. Data analysis was performed from January to September 2022. Exposures: Disability status, including physical (spinal cord injury or mobility impairment), sensory (visual or hearing impairments), developmental (intellectual or developmental disability or autism), and cognitive (traumatic brain injury) disabilities. Main Outcomes and Measures: The main outcomes were National Quality Forum–endorsed quality measures: (1) use of MOUD (buprenorphine, methadone, or naltrexone) during each study year and (2) 6-month continuity of treatment (for those taking MOUD). Results: A total of 84 728 Washington Medicaid enrollees had claims evidence of OUD, representing 159 591 person-years (84 762 person-years [53.1%] for female participants, 116 145 person-years [72.8%] for non-Hispanic White participants, and 100 970 person-years [63.3%] for participants aged 18-39 years); 15.5% of the population (24 743 person-years) had evidence of a physical, sensory, developmental, or cognitive disability. PWD were 40% less likely than those without a disability to receive any MOUD (adjusted odds ratio, 0.60; 95% CI, 0.58-0.61; P < .001). This was true for each disability type, with variations. Individuals with a developmental disability were least likely to use MOUD (AOR, 0.50; 95% CI, 0.46-0.55; P < .001). Of those using MOUD, PWD were 13% less likely than people without disability to continue MOUD for 6 months (adjusted OR, 0.87; 95% CI, 0.82-0.93; P < .001). Conclusions and Relevance: In this case-control study of a Medicaid population, treatment differences were found between PWD and people without these disabilities; these differences cannot be explained clinically and highlight inequities in treatment. Policies and interventions to increase MOUD access are critical to reducing morbidity and mortality among PWD. Potential solutions include improved enforcement of the Americans with Disabilities Act, workforce best practice training, and addressing stigma, accessibility, and the need for accommodations to improve OUD treatment for PWD.

Introduction

Although the US federal government declared the opioid crisis a public health emergency in 2017, there were more than 100 000 drug overdose deaths in 2021, with more than 70% involving opioids. Medications to treat opioid use disorder (OUD) are effective, yet underused. Studies have revealed inequities in OUD treatment by race, ethnicity, gender, and socioeconomic status, but only limited investigation regarding access to or quality of OUD treatment is specific to people with disabilities (PWD). PWD account for 26% of the US population, and health equity is a demonstrated concern, because PWD experience barriers to health care overall.

Importantly, PWD are at heightened risk of OUD. They are more likely to experience acute and chronic pain, which have been key factors associated with prescription opioid use in the US. In addition, PWD have increased risk factors for substance use disorders (SUDs), such as higher rates of mental disorders and adverse social determinants of health, and increased risk of opioid-related consequences and overdose deaths. However, PWD may misuse prescription opioids to relieve pain, suggesting that they are receiving inadequate pain management. Certain PWD subgroups have higher risk of opioid misuse and opioid-related consequences, although findings are not consistent. People with a history of traumatic brain injury (TBI), who are more likely to receive opioids than those without TBI, have greater risk for opioid misuse and overdose. Despite these reports, research examining OUD treatment is lacking for PWD.

Three medications for OUD (MOUD) are approved by the US Food and Drug Administration (buprenorphine, methadone, and naltrexone). Buprenorphine and methadone are associated with reduced risk of overdose compared with only psychosocial interventions, but naltrexone is not. However, MOUD is underused. A study of Medicaid enrollees in 11 states found that only 55% of individuals with OUD were receiving MOUD; adults enrolled in Medicaid because of categorical disability were less likely to be receiving MOUD than adult Medicaid enrollees without disability. Regardless of disability status, less than 60% of those receiving MOUD continued treatment for at least 6 months, a recommended minimum period demonstrating continuity and an important quality indicator. These findings reveal inequities in MOUD use for persons enrolled in Medicaid because of disability; however, we do not know whether inequities persist for a broader group of adults with disabling conditions as diagnosed by clinicians.

Barriers to OUD treatment are common, and many people with OUD are not treated. PWD experience additional barriers to SUD treatment, including stigma, inaccessible facilities and materials, difficulty accessing reliable transportation, and lack of staff disability training. Each type of Food and Drug Administration–approved MOUD has different requirements for use (eg, methadone generally requires daily in-person dispensing, whereas buprenorphine is usually prescribed); thus, each may present unique barriers for PWD that affect use and continuity.

A gap in knowledge remains regarding inequities in initiating and continuing MOUD treatment by disability status, key quality indicators of OUD treatment. This case-control study examines MOUD use and continuity, by disability status and type, among Medicaid-enrolled adults with OUD in Washington State compared with Medicaid-enrolled adults with no evidence of the specified disability. Administrative claims data allow examination of treatment differences between individuals who have been identified by clinicians as having a disability and those without such evidence. The study’s findings are of critical importance to clinicians, policy makers, and people with co-occurring disability and OUD, to improve health and reduce inequities and OUD-related consequences for PWD.

Methods

Data and Study Population

The study was approved by the Brandeis University institutional review board and was deemed exempt for the need for informed consent by the Washington State Department of Social and Health Services institutional review board because the data were deidentified, in accordance with 45 CFR §46. The report follows the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) reporting guideline for case-control studies. We examined Medicaid outpatient, inpatient, residential, and pharmacy claims from Washington State for 2016 to 2019. Using a clinically driven approach, we captured people who may not have been administratively deemed to have a disability for access to income supports and Medicaid, but who had reached a clinical threshold for diagnosis. Washington is a Medicaid expansion state, with a full continuum of SUD care, including all types of MOUD. For each year, we included adults aged 18 to 64 years with an OUD diagnosis who were continuously eligible for full Medicaid benefits for 12 months, to observe full service use. We defined OUD as at least 1 claim for outpatient, inpatient, or residential services with an OUD diagnosis code in a calendar year (eTable 1 in Supplement 1). We excluded 2587 people eligible for both Medicare and Medicaid because Medicare services were unobservable, 1132 people with a benzodiazepine prescription during the same year because concurrent MOUD is associated with increased risk of adverse effects, and 132 people because prescription days supply was missing (eFigure in Supplement 1). Analyses of MOUD treatment continuity required continuous 6 months of data following the first evidence of MOUD, requiring a look back for claims occurring in the first week of the year to see whether they were the end of an earlier episode.

Outcome Measures

We examined use and continuity of MOUD treatment according to National Quality Forum (NQF)–endorsed measures, which many states use for Medicaid monitoring and reporting. Any MOUD use during a calendar year for patients with OUD (NQF No. 3400) is defined as having at least 1 MOUD claim during the year, overall and by type of medication. The 3 types of MOUD were identified using prescription drug data and medical procedure codes (eTable 2 in Supplement 1). The continuity measure represents continuous medication treatment for at least 6 months for those patients using MOUD (NQF No. 3175). Continuity was defined as evidence of MOUD use for 6 months after an index MOUD claim, without a 7-day gap. Full specifications for utilization and continuity are included in the eAppendix in Supplement 1.

Disability and Types of Disability

This study used diagnosis codes to identify 4 common types of disabling conditions: physical (eg, spinal cord injuries and mobility impairment), sensory (eg, blind or visual impairments, and deaf or hard of hearing), developmental (eg, Down syndrome, autism, and other intellectual or developmental disabilities), and cognitive (ie, TBI). See eTable 3 in Supplement 1 for diagnostic codes. These conditions were informed by the US Census Bureau’s American Community Survey standardized disability types and by their association with increased risk for SUD. Each disability type was indicated through a dichotomous variable. A summary variable indicated the presence of any of these disabling conditions. Because a considerable body of research focuses on OUD treatment for individuals with co-occurring substance use and mental disorders, we did not examine these groups separately.

Statistical Analysis

Data analysis was performed from January to September 2022. Analyses were conducted by person-year. After conducting descriptive analyses and χ2 tests, we fit generalized estimating equations with robust SEs assuming an exchangeable correlation structure using SAS statistical software version 9.4 (SAS Institute) to account for correlated outcomes of individuals in the data for multiple years. Two-tailed P < .05 was considered to denote statistical significance. Models adjusted for the confounding variables of age, gender, race and ethnicity (identified via database; race and ethnicity were included to isolate their associations with disability to the extent possible), urban residence, SUD other than OUD in the year, mental disorder in the year, eligibility year, and living in an institution for at least 2 months of the year, to be consistent with the literature. Model 1 included any disability as a dichotomous independent variable. Model 2 included each type of disability, also dichotomous with each compared with persons without that disability, as some enrollees have more than 1 type. Full models are in eTables 4, 5, 6, and 7 in Supplement 1. We also modeled type of medication by disability status and type among those receiving buprenorphine or methadone.

Results

The sample for MOUD use analyses included 84 728 people, representing 159 591 person-years (84 762 person-years [53.1%] for female participants, 116 145 person-years [72.8%] for non-Hispanic White participants, and 100 970 person-years [63.3%] for participants aged 18-39 years). Table 1 shows sample characteristics overall and by any disability. People with the included disabling conditions represented 24 743 person-years (15.5%). Nearly half of the disability sample had a cognitive disability or TBI (11 834 person-years [47.8%]), and more than one-quarter had a physical (7304 person-years [29.5%]) or sensory (6562 person-years [26.5%]) disability. Compared with people without disability, PWD were older and more often had a mental disorder.

Table 1

Unadjusted MOUD use was lower for PWD than for people without disability (9438 person-years [38.1%] vs 73 778 person-years [54.7%]) (Table 2). Unadjusted MOUD rates were lowest for people with physical (2271 person-years [31.1%]) or developmental (1027 person-years [32.9%]) disability and highest for people with cognitive disability (5075 person-years [42.9%]), but all were lower than for individuals with no disability. Both buprenorphine and methadone were less often prescribed or administered for PWD than for those without disability (buprenorphine, 4608 person-years [18.6%] vs 36 865 person-years [27.3%]; methadone, 3634 person-years [14.7%] vs 29 381 person-years [21.8%]). Naltrexone use was low in both populations, at 2.2% (534 PWD and 2905 people without disability). Rates of buprenorphine and methadone use were similar, ranging between 13.0% and 15.7%, except for people with cognitive disability, who used buprenorphine more often than methadone (2578 person-years [21.8%] vs 1777 person-years [15.0%]). Over time, unadjusted MOUD use increased overall from 39.2% (14 757 person-years) in 2016 to 64.1% (26 560 person-years) in 2019, but the difference between PWD and persons without disability remained consistent and significant (Figure).

Table 2Figure

The adjusted odds of receiving MOUD were 40% lower for PWD than for people without disability (model 1 adjusted odds ratio [AOR], 0.60; 95% CI, 0.58-0.61; P < .001) (Table 3). The presence of each type of disability was associated with lower MOUD use, compared with people without that disability, with differences by type of disability (model 2). Among PWD, individuals with cognitive disability were most likely to use MOUD (AOR, 0.77; 95% CI, 0.74-0.80; P < .001), and individuals with developmental disability had the lowest odds of MOUD use (AOR, 0.50; 95% CI, 0.46-0.55; P < .001). Among MOUD recipients, we found no difference in the likelihood of receiving buprenorphine vs methadone by overall disability status (eTables 8 and 9 in Supplement 1). However, individuals with developmental disability were less likely to receive buprenorphine than methadone.

Table 3

Analyses for MOUD continuity were limited to 2017 and 2018 and included 27 688 people representing 40 550 person-years. For people using MOUD, unadjusted rates (Table 3) show that PWD met the 6-month threshold for continuous MOUD less often than persons without disabilities (2199 person-years [46.3%] vs 17 913 person-years [50.0%]); those with cognitive disability had the lowest MOUD continuity rate (1113 person-years [44.2%]), and those with sensory disability had the highest continuity rate (590 person-years [51.6%]). Table 4 shows the adjusted difference in MOUD continuity by disability. People with any disability were 13% less likely than those without disability to continuously use MOUD over 6 months (model 1 AOR, 0.87; 95% CI, 0.82-0.93; P < .001). Individuals with a physical disability (model 2 AOR, 0.85; 95% CI, 0.74-0.96; P = .009) or cognitive disability (model 2 AOR, 0.89; 95% CI, 0.82-0.97; P = .006) were less likely than people without those conditions to continue MOUD for 6 months. Continuity did not differ for people with developmental or sensory disability vs people without those conditions.

Table 4

Discussion

The findings reported in this case-control study highlight inequities in MOUD treatment use among PWD compared with people with none of these common disabling conditions (40% less likely to use MOUD), with less disparity observed for MOUD continuity; PWD were 13% less likely than people without disability to use MOUD continuously for 6 months. These large inequities in MOUD use persisted throughout the study window and were present for each type of disabling condition examined. Differences by disability type were minor, suggesting that there are systematic barriers to initiating treatment for PWD, regardless of type of disability, compared with people without disabilities. Once taking MOUD, the differences in continuity between people with and without disability were smaller and, in some cases, insignificant. Thus, addressing inequities in initiating MOUD for PWD is most critical.

Our findings regarding MOUD use are consistent with the 11-state Medicaid study by Donohue et al,2 which found that individuals with OUD who were categorically eligible for Medicaid enrollment because of disability were less likely than adults without disability to use MOUD. However, the earlier study did not identify differences in continuity rates we found between PWD and people without disability, and those authors defined disability by the Medicaid categorical determination and did not consider types of disability. To our knowledge, our data are the first to examine MOUD use and continuity among persons with diagnosed potentially disabling conditions. This approach allows analysis of a larger group of patients beyond those categorically eligible for Medicaid, eliminates issues with eligibility determinations that exclude those who did not apply for or did not qualify as disabled according to employment-based guidelines, and allows a focus on disability type. We identified PWD through clinically assigned diagnoses, which factor in clinical assessments and recommendations for services. Differences by disability status in this population indicate disparities in OUD treatment quality that extend to PWD with a range of disability types. By focusing on specific types of disabilities, potential implications for policy and practice emerge.

These inequities in MOUD use and continuity cannot be explained clinically and may reflect limited access or bias in treatment approaches for PWD, which has also been identified in care not specific to OUD. PWD may have more medically complex conditions, yet there are no medical contraindications to using MOUD for PWD that justify this consistent disparity. Practitioners may be wary of MOUD for PWD who also have pain, and patients, in turn, may worry that OUD treatment will lead to inadequate pain management. To the extent that SUD treatment practitioners are unfamiliar with complex needs of PWD, practitioners may be reluctant to engage with them. For example, people with complex activity limitations are less likely than their peers without disability to report that practitioners listened carefully, showed respect, or explained things in an understandable way. Furthermore, only 41% of practicing US physicians reported feeling very confident about their ability to provide the same quality of care for PWD as patients without disability, and only approximately one-half reported strongly welcoming PWD into their practice. Other practitioner beliefs may play a role, such as PWD seeming to be noncompliant with treatment (vs requiring alternative means of engaging).

For PWD, we found inequities in both methadone and buprenorphine use, with naltrexone used rarely. Barriers highlighted by these inequities may be related to type of MOUD, although we did not find that any 1 type of MOUD was consistently used more than another for PWD overall.

Continuity of MOUD treatment was lower for people with physical and cognitive disabilities, suggesting a potential lack of accommodations by practitioners. For people with physical disabilities, accessibility may be an ongoing burden. The finding of reduced MOUD continuity for persons with cognitive disability as defined here highlights the perfect storm model of cascading vulnerabilities for persons with TBI, for whom cognitive difficulties may lead to greater challenges in engaging with treatment. Although it might be expected that people with developmental or sensory disabilities would experience similar difficulties with ongoing treatment engagement, they had rates of MOUD continuity comparable to those for people without those conditions. This may indicate that for these individuals, once MOUD is started, remaining in treatment is less burdensome. These findings of large inequities in MOUD use and more limited inequities in continuity highlight the importance of focusing on initiating treatment as a major barrier to overcome. However, the inequities in MOUD continuity may reflect similar concerns around accessibility and stigma. Further research is needed to better understand the nuances of these findings.

Structural barriers may be substantial for PWD, regardless of MOUD type. The Americans with Disabilities Act (ADA) mandates accessibility, but not all practitioners comply. The last reported data, from more than a decade ago, found that many SUD treatment programs were not fully physically accessible (eg, narrow doorways or lacked ramps or elevators). Moreover, accessibility goes beyond physical means, to include offering materials and interventions that are accessible to people with visual or hearing impairments or with developmental, intellectual, or cognitive disabilities. Structural barriers imply that PWD are not welcome, and, thus, PWD may be unlikely to start treatment.

The intersecting stigma of disability and SUD heightens barriers to OUD treatment for PWD. Negative attitudes toward people with drug addiction are wide-ranging and common. PWD may experience additional challenges in seeking OUD treatment because of negative stereotypes and stigma associated with disability. Additional intersectionality (eg, race and ethnicity, gender, and mental disorders) may also play a role. Efforts to develop policies and interventions to reduce stigma and increase use of MOUD for PWD are critical to reducing future morbidity and mortality among this population, which often experiences health inequities. Efforts to improve access to MOUD should incorporate low-barrier and accessible approaches to treatment. This includes same-day treatment, wide availability of MOUD in accessible locations, and telemedicine options. Practitioner awareness of the unique challenges experienced by PWD is important, and workforce training, regarding both disability and OUD, is essential to ensuring PWD are screened for OUD and referred to MOUD. Efforts to improve access to MOUD for PWD should be implemented as part of wider efforts to educate practitioners and the community to reduce stigma around OUD and MOUD, such as through stigma reduction campaigns and engagement of regulatory and accreditation agencies.

A 2-fold approach is essential for training practitioners. Practitioners who frequently engage with PWD, particularly via primary care, specialty care, and rehabilitation, should be trained to screen for OUD, be knowledgeable about MOUD treatment effectiveness, and refer patients for treatment regardless of disability status. In addition, practitioners must understand disability within their patient population and the importance of accommodations. It is essential to identify best practices for PWD specific to OUD screening and treatment, reasonable accommodation strategies, and legal obligations under the ADA. A person-centered approach is essential to reduce the inequities we observed in our study.

Strengths and Limitations

A strength of this study is that we were able to examine types of disability and types of MOUD across a Medicaid population. However, similar to other studies using diagnosis codes to identify PWD, there are also limitations. Diagnosis-identified disabling conditions are not synonymous with functional disability but are a clinically based recognition that the patient has a potentially disabling condition that should be considered in the context of care. We examined 4 broad categories of disabling conditions; some people in the no-disability category might have these conditions but were not identified if the conditions were not recorded in the billing for a medical encounter, and some people may have other disabling conditions, making our estimates conservative. Furthermore, there are likely interaction effects of comorbidities or other factors with disability, which should be examined in further research. We chose 2 well-validated process measures of quality OUD care, but there are additional measures that may indicate disparities in care (eg, emergency department visits or opioid-related hospitalizations). We do not know patients’ history of opioid use, or whether some patients may have taken home medications. In addition, the results of this study may not be generalizable to commercially insured or Medicare populations or to Medicaid populations that are not continuously enrolled.

Conclusions

The findings of this case-control study suggest that PWD are at greater risk of OUD than persons without disability and have more risk of SUD and adverse consequences, but are less likely to use and maintain essential treatment for OUD. Addressing the MOUD initiation gap could reduce treatment inequities. Several structural challenges exist that can be addressed by policy actions and practitioner and community education, including enforcement of ADA requirements, efforts to promote low-barrier care, and education of practitioners and community members to mitigate the heightened stigma associated with having both a disability and OUD.

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Abstract

Importance: Adverse outcomes associated with opioid use disorder (OUD) are disproportionately high among people with disabilities (PWD) compared with those without disability. A gap remains in understanding the quality of OUD treatment for people with physical, sensory, cognitive, and developmental disabilities, specifically regarding medications for OUD (MOUD), a foundation of treatment. Objective: To examine the use and quality of OUD treatment in adults with diagnosed disabling conditions, compared with adults without these diagnoses. Design, Setting, and Participants: This case-control study used Washington State Medicaid data from 2016 to 2019 (for use) and 2017 to 2018 (for continuity). Data were obtained for outpatient, residential, and inpatient settings with Medicaid claims. Participants included Washington State full-benefit Medicaid enrollees aged 18 to 64 years, continuously eligible for 12 months, with OUD during the study years and not enrolled in Medicare. Data analysis was performed from January to September 2022. Exposures: Disability status, including physical (spinal cord injury or mobility impairment), sensory (visual or hearing impairments), developmental (intellectual or developmental disability or autism), and cognitive (traumatic brain injury) disabilities. Main Outcomes and Measures: The main outcomes were National Quality Forum–endorsed quality measures: (1) use of MOUD (buprenorphine, methadone, or naltrexone) during each study year and (2) 6-month continuity of treatment (for those taking MOUD). Results: A total of 84 728 Washington Medicaid enrollees had claims evidence of OUD, representing 159 591 person-years (84 762 person-years [53.1%] for female participants, 116 145 person-years [72.8%] for non-Hispanic White participants, and 100 970 person-years [63.3%] for participants aged 18-39 years); 15.5% of the population (24 743 person-years) had evidence of a physical, sensory, developmental, or cognitive disability. PWD were 40% less likely than those without a disability to receive any MOUD (adjusted odds ratio, 0.60; 95% CI, 0.58-0.61; P < .001). This was true for each disability type, with variations. Individuals with a developmental disability were least likely to use MOUD (AOR, 0.50; 95% CI, 0.46-0.55; P < .001). Of those using MOUD, PWD were 13% less likely than people without disability to continue MOUD for 6 months (adjusted OR, 0.87; 95% CI, 0.82-0.93; P < .001). Conclusions and Relevance: In this case-control study of a Medicaid population, treatment differences were found between PWD and people without these disabilities; these differences cannot be explained clinically and highlight inequities in treatment. Policies and interventions to increase MOUD access are critical to reducing morbidity and mortality among PWD. Potential solutions include improved enforcement of the Americans with Disabilities Act, workforce best practice training, and addressing stigma, accessibility, and the need for accommodations to improve OUD treatment for PWD.

Summary

A significant disparity exists in Medication for Opioid Use Disorder (MOUD) treatment access and continuity among adults with disabilities (PWD) compared to their non-disabled counterparts. This case-control study, utilizing Washington State Medicaid claims data (2016-2019), investigated MOUD utilization and continuity amongst adults with OUD, stratified by disability type (physical, sensory, developmental, cognitive). The study employed a clinically driven approach to identify PWD, ensuring capture of individuals who may not have been administratively classified as disabled.

Data and Study Population

The study, approved by relevant Institutional Review Boards, adhered to STROBE guidelines. Data encompassed Medicaid claims (outpatient, inpatient, residential, pharmacy). The study population consisted of adults (18-64 years) with continuous full Medicaid eligibility for 12 months and at least one OUD diagnosis claim. Exclusion criteria included dual Medicare/Medicaid eligibility, concurrent benzodiazepine prescription, and missing prescription data. The analysis utilized a person-year approach.

Outcome Measures

MOUD use was defined as at least one MOUD claim per calendar year (NQF No. 3400). Continuity was measured as uninterrupted MOUD use for at least six months post-index claim (NQF No. 3175). Three MOUD types (buprenorphine, methadone, naltrexone) were identified via prescription and procedure codes.

Disability and Types of Disability

Four disability categories were defined using diagnostic codes: physical, sensory, developmental, and cognitive. These categories aligned with US Census Bureau classifications and SUD risk associations. A composite variable indicated the presence of any disability. Mental health comorbidities were not analyzed separately.

Statistical Analysis

Generalized estimating equations (GEE) with robust standard errors were employed to account for correlated outcomes. Confounding variables (age, gender, race/ethnicity, urban residence, other SUDs, mental disorders, eligibility year, institutionalization) were adjusted for in two models: Model 1 (any disability) and Model 2 (specific disability types). Statistical significance was defined as P < .05.

Results

The study sample comprised 84,728 individuals (159,591 person-years). PWD represented 15.5% of the person-years. Unadjusted MOUD use was significantly lower for PWD (38.1%) than non-disabled individuals (54.7%). Adjusted analyses revealed a 40% lower odds of MOUD initiation for PWD (AOR 0.60, P < .001). Each disability type showed lower MOUD use compared to the respective non-disabled group. MOUD continuity analysis (2017-2018) indicated a 13% lower odds of six-month continuous MOUD use for PWD (AOR 0.87, P < .001).

Discussion

The observed disparities in MOUD initiation and continuity are not attributable to clinical factors, but rather to systemic access barriers and potential biases in treatment approaches for PWD. These findings underscore the urgent need for targeted interventions to improve MOUD access and reduce stigma surrounding both OUD and disability.

Strengths and Limitations

The study’s strengths include its examination of various disability and MOUD types within a large Medicaid population. Limitations include reliance on diagnostic codes for disability identification, potential underestimation of PWD due to incomplete diagnostic coding, and the potential for unmeasured confounding factors. The findings may not be generalizable beyond the study population.

Conclusions

PWD face significant barriers to accessing and maintaining MOUD treatment. Addressing these inequities requires a multi-faceted approach encompassing policy changes, enhanced practitioner training (including ADA compliance and disability awareness), community education, and the promotion of low-barrier, accessible treatment options.

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Abstract

Importance: Adverse outcomes associated with opioid use disorder (OUD) are disproportionately high among people with disabilities (PWD) compared with those without disability. A gap remains in understanding the quality of OUD treatment for people with physical, sensory, cognitive, and developmental disabilities, specifically regarding medications for OUD (MOUD), a foundation of treatment. Objective: To examine the use and quality of OUD treatment in adults with diagnosed disabling conditions, compared with adults without these diagnoses. Design, Setting, and Participants: This case-control study used Washington State Medicaid data from 2016 to 2019 (for use) and 2017 to 2018 (for continuity). Data were obtained for outpatient, residential, and inpatient settings with Medicaid claims. Participants included Washington State full-benefit Medicaid enrollees aged 18 to 64 years, continuously eligible for 12 months, with OUD during the study years and not enrolled in Medicare. Data analysis was performed from January to September 2022. Exposures: Disability status, including physical (spinal cord injury or mobility impairment), sensory (visual or hearing impairments), developmental (intellectual or developmental disability or autism), and cognitive (traumatic brain injury) disabilities. Main Outcomes and Measures: The main outcomes were National Quality Forum–endorsed quality measures: (1) use of MOUD (buprenorphine, methadone, or naltrexone) during each study year and (2) 6-month continuity of treatment (for those taking MOUD). Results: A total of 84 728 Washington Medicaid enrollees had claims evidence of OUD, representing 159 591 person-years (84 762 person-years [53.1%] for female participants, 116 145 person-years [72.8%] for non-Hispanic White participants, and 100 970 person-years [63.3%] for participants aged 18-39 years); 15.5% of the population (24 743 person-years) had evidence of a physical, sensory, developmental, or cognitive disability. PWD were 40% less likely than those without a disability to receive any MOUD (adjusted odds ratio, 0.60; 95% CI, 0.58-0.61; P < .001). This was true for each disability type, with variations. Individuals with a developmental disability were least likely to use MOUD (AOR, 0.50; 95% CI, 0.46-0.55; P < .001). Of those using MOUD, PWD were 13% less likely than people without disability to continue MOUD for 6 months (adjusted OR, 0.87; 95% CI, 0.82-0.93; P < .001). Conclusions and Relevance: In this case-control study of a Medicaid population, treatment differences were found between PWD and people without these disabilities; these differences cannot be explained clinically and highlight inequities in treatment. Policies and interventions to increase MOUD access are critical to reducing morbidity and mortality among PWD. Potential solutions include improved enforcement of the Americans with Disabilities Act, workforce best practice training, and addressing stigma, accessibility, and the need for accommodations to improve OUD treatment for PWD.

Summary

This study investigated inequities in medication-assisted treatment (MAT) for opioid use disorder (OUD) among people with disabilities (PWD) enrolled in Washington State Medicaid. Researchers analyzed Medicaid claims data from 2016-2019, focusing on MAT use and continuity, categorized by disability type (physical, sensory, developmental, cognitive). The study found significant disparities in MAT initiation for PWD compared to those without disabilities, persisting across disability types and medication types. While continuity of treatment showed less disparity, gaps remained, particularly for those with physical and cognitive disabilities. The findings highlight the need for policy changes and increased practitioner awareness to address barriers to MAT access and improve health equity for PWD with OUD.

Data and Study Population

The study utilized Washington State Medicaid claims data (2016-2019) on adults (18-64) with OUD diagnoses and continuous Medicaid eligibility for 12 months. OUD was defined by at least one claim for outpatient, inpatient, or residential services with an OUD diagnosis code. Exclusions included individuals with dual Medicare/Medicaid eligibility, concurrent benzodiazepine prescriptions, and missing prescription data. The study employed a clinically driven approach to identify PWD, going beyond administrative disability designations to include those clinically diagnosed with specific disabling conditions. This broadened the scope beyond individuals receiving income support due to disability.

Outcome Measures

The study employed National Quality Forum (NQF)-endorsed measures to assess MAT use and continuity. MAT use was defined as at least one MAT claim during a calendar year. Continuity was defined as continuous MAT use for at least six months after an index claim, without a seven-day gap. Three types of MAT (buprenorphine, methadone, naltrexone) were identified using prescription drug and procedure codes.

Disability and Types of Disability

Four common disability types were examined: physical, sensory, developmental, and cognitive. These categories align with US Census Bureau classifications and known associations with increased SUD risk. Diagnostic codes were used to identify each type, with a summary variable indicating the presence of any of these conditions. Co-occurring mental health disorders were not analyzed separately due to existing research in this area.

Statistical Analysis

Data analysis (January-September 2022) used person-year analysis. Descriptive analyses, χ² tests, and generalized estimating equations (GEE) with robust standard errors were employed to account for correlated outcomes. Models adjusted for age, gender, race/ethnicity, urban residence, other SUDs, mental disorders, eligibility year, and institutionalization. Model 1 assessed overall disability status, while Model 2 examined each disability type separately. A P value < .05 denoted statistical significance.

Results

The study sample encompassed 84,728 individuals, representing 159,591 person-years. PWD represented 15.5% of person-years, with cognitive/TBI being the most prevalent disability type. Unadjusted analyses revealed lower MAT use among PWD compared to non-PWD. Adjusted analyses confirmed a 40% lower odds of receiving MAT among PWD (Model 1). Model 2 showed lower MAT odds for each disability type compared to their non-disabled counterparts, with developmental disability showing the lowest odds. MAT continuity analyses (2017-2018) showed a 13% lower likelihood of six-month continuous MAT use among PWD (Model 1). Model 2 identified reduced continuity for individuals with physical and cognitive disabilities.

Discussion

The study’s findings underscore substantial inequities in MAT access for PWD. These disparities are not fully explained by clinical factors, suggesting potential barriers related to access, bias, and practitioner familiarity with the complex needs of PWD. The study highlights the importance of addressing initiation barriers rather than solely focusing on treatment continuation. Structural barriers (e.g., inaccessible facilities, lack of accommodations), stigma, and practitioner attitudes are discussed as contributing factors.

Strengths and Limitations

Strengths include examination of disability types and MAT types within a large Medicaid population. Limitations include reliance on diagnosis codes (not equivalent to functional disability), potential exclusion of PWD without recorded diagnoses, and the lack of data on factors like opioid use history. The findings may not be generalizable to other insurance populations or Medicaid populations with non-continuous enrollment.

Conclusions

This study demonstrates significant inequities in MAT access and continuity for PWD with OUD. Addressing these inequities requires a multifaceted approach including policy changes (e.g., ADA enforcement), improved access to low-barrier care, and targeted education for practitioners and the community to reduce stigma. A person-centered approach is crucial for reducing these observed disparities.

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Abstract

Importance: Adverse outcomes associated with opioid use disorder (OUD) are disproportionately high among people with disabilities (PWD) compared with those without disability. A gap remains in understanding the quality of OUD treatment for people with physical, sensory, cognitive, and developmental disabilities, specifically regarding medications for OUD (MOUD), a foundation of treatment. Objective: To examine the use and quality of OUD treatment in adults with diagnosed disabling conditions, compared with adults without these diagnoses. Design, Setting, and Participants: This case-control study used Washington State Medicaid data from 2016 to 2019 (for use) and 2017 to 2018 (for continuity). Data were obtained for outpatient, residential, and inpatient settings with Medicaid claims. Participants included Washington State full-benefit Medicaid enrollees aged 18 to 64 years, continuously eligible for 12 months, with OUD during the study years and not enrolled in Medicare. Data analysis was performed from January to September 2022. Exposures: Disability status, including physical (spinal cord injury or mobility impairment), sensory (visual or hearing impairments), developmental (intellectual or developmental disability or autism), and cognitive (traumatic brain injury) disabilities. Main Outcomes and Measures: The main outcomes were National Quality Forum–endorsed quality measures: (1) use of MOUD (buprenorphine, methadone, or naltrexone) during each study year and (2) 6-month continuity of treatment (for those taking MOUD). Results: A total of 84 728 Washington Medicaid enrollees had claims evidence of OUD, representing 159 591 person-years (84 762 person-years [53.1%] for female participants, 116 145 person-years [72.8%] for non-Hispanic White participants, and 100 970 person-years [63.3%] for participants aged 18-39 years); 15.5% of the population (24 743 person-years) had evidence of a physical, sensory, developmental, or cognitive disability. PWD were 40% less likely than those without a disability to receive any MOUD (adjusted odds ratio, 0.60; 95% CI, 0.58-0.61; P < .001). This was true for each disability type, with variations. Individuals with a developmental disability were least likely to use MOUD (AOR, 0.50; 95% CI, 0.46-0.55; P < .001). Of those using MOUD, PWD were 13% less likely than people without disability to continue MOUD for 6 months (adjusted OR, 0.87; 95% CI, 0.82-0.93; P < .001). Conclusions and Relevance: In this case-control study of a Medicaid population, treatment differences were found between PWD and people without these disabilities; these differences cannot be explained clinically and highlight inequities in treatment. Policies and interventions to increase MOUD access are critical to reducing morbidity and mortality among PWD. Potential solutions include improved enforcement of the Americans with Disabilities Act, workforce best practice training, and addressing stigma, accessibility, and the need for accommodations to improve OUD treatment for PWD.

Summary

The opioid crisis continues to be a major public health issue in the US, with a disproportionate impact on people with disabilities (PWD). PWD face numerous barriers to accessing and maintaining medication for opioid use disorder (OUD), including stigma, inaccessible facilities, and a lack of practitioner training. This study examines medication use and treatment continuity among Medicaid-enrolled adults with OUD in Washington State, comparing those with and without disabilities.

Data and Study Population

Researchers analyzed Medicaid claims data from Washington State (2016-2019) for adults (18-64) with OUD. They defined OUD based on medical claims and excluded individuals with Medicare or concurrent benzodiazepine prescriptions. The study included four common disability types: physical, sensory, developmental, and cognitive.

Outcome Measures

The study assessed MOUD (Medication for Opioid Use Disorder) use (any MOUD claim in a year) and continuity (continuous use for at least six months). Three types of MOUD—buprenorphine, methadone, and naltrexone—were analyzed.

Disability and Types of Disability

Four disability categories were used: physical, sensory, developmental, and cognitive. A person could have more than one disability.

Statistical Analysis

Data analysis used generalized estimating equations to account for multiple years of data per individual. Models adjusted for age, gender, race, ethnicity, urban residence, other SUDs, mental health disorders, eligibility year, and institutional living.

Results

PWD were less likely to use MOUD (38.1% vs 54.7% in the non-disabled group) and less likely to maintain continuous treatment for six months (46.3% vs 50.0%). These disparities were consistent across all disability types. While the type of MOUD did not significantly affect the overall disparity, individuals with developmental disabilities were less likely to receive buprenorphine than methadone.

Discussion

The lower rates of MOUD use among PWD aren't fully explained by medical factors but likely reflect access barriers and biases in treatment approaches. Lack of practitioner training and understanding of the needs of PWD are significant contributing factors, alongside accessibility issues and stigma.

Strengths and Limitations

A strength is the examination of various disability and MOUD types within a large Medicaid population. Limitations include reliance on diagnostic codes, potential for unrecorded conditions, and the possibility of unobserved interactions between comorbidities and disability. The study's findings may not be generalizable to all populations.

Conclusions

PWD face significant barriers to accessing and maintaining OUD treatment. Addressing these barriers requires policy changes, practitioner training, and community education to improve access and reduce stigma.

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Abstract

Importance: Adverse outcomes associated with opioid use disorder (OUD) are disproportionately high among people with disabilities (PWD) compared with those without disability. A gap remains in understanding the quality of OUD treatment for people with physical, sensory, cognitive, and developmental disabilities, specifically regarding medications for OUD (MOUD), a foundation of treatment. Objective: To examine the use and quality of OUD treatment in adults with diagnosed disabling conditions, compared with adults without these diagnoses. Design, Setting, and Participants: This case-control study used Washington State Medicaid data from 2016 to 2019 (for use) and 2017 to 2018 (for continuity). Data were obtained for outpatient, residential, and inpatient settings with Medicaid claims. Participants included Washington State full-benefit Medicaid enrollees aged 18 to 64 years, continuously eligible for 12 months, with OUD during the study years and not enrolled in Medicare. Data analysis was performed from January to September 2022. Exposures: Disability status, including physical (spinal cord injury or mobility impairment), sensory (visual or hearing impairments), developmental (intellectual or developmental disability or autism), and cognitive (traumatic brain injury) disabilities. Main Outcomes and Measures: The main outcomes were National Quality Forum–endorsed quality measures: (1) use of MOUD (buprenorphine, methadone, or naltrexone) during each study year and (2) 6-month continuity of treatment (for those taking MOUD). Results: A total of 84 728 Washington Medicaid enrollees had claims evidence of OUD, representing 159 591 person-years (84 762 person-years [53.1%] for female participants, 116 145 person-years [72.8%] for non-Hispanic White participants, and 100 970 person-years [63.3%] for participants aged 18-39 years); 15.5% of the population (24 743 person-years) had evidence of a physical, sensory, developmental, or cognitive disability. PWD were 40% less likely than those without a disability to receive any MOUD (adjusted odds ratio, 0.60; 95% CI, 0.58-0.61; P < .001). This was true for each disability type, with variations. Individuals with a developmental disability were least likely to use MOUD (AOR, 0.50; 95% CI, 0.46-0.55; P < .001). Of those using MOUD, PWD were 13% less likely than people without disability to continue MOUD for 6 months (adjusted OR, 0.87; 95% CI, 0.82-0.93; P < .001). Conclusions and Relevance: In this case-control study of a Medicaid population, treatment differences were found between PWD and people without these disabilities; these differences cannot be explained clinically and highlight inequities in treatment. Policies and interventions to increase MOUD access are critical to reducing morbidity and mortality among PWD. Potential solutions include improved enforcement of the Americans with Disabilities Act, workforce best practice training, and addressing stigma, accessibility, and the need for accommodations to improve OUD treatment for PWD.

Summary

In 2021, many people died from drug overdoses, and many involved opioids. Even though there are good medicines to help people with opioid problems, many people aren't getting them. People with disabilities have an even harder time getting help. This study looks at why.

Data and Study Population

Researchers looked at health records from Washington State to see how many adults with opioid problems also had disabilities. They wanted to see if people with disabilities were getting the medicines they needed to get better. They only looked at people who got their health care paid for by Medicaid and had a full year of records.

Outcome Measures

Researchers checked to see if people were using the medicine and if they kept using it for at least six months.

Disability and Types of Disability

The study looked at four types of disabilities: physical, sensory, developmental, and cognitive. Cognitive disabilities include things like brain injuries. A person could have more than one disability.

Statistical Analysis

The researchers used special math to compare people with and without disabilities. They made sure to consider things like age, gender, and other health problems that could affect the results.

Results

People with disabilities were less likely to get the medicine than people without disabilities. This was true for all types of disabilities. Those with disabilities also tended to stop taking the medicine sooner.

Discussion

The study showed that people with disabilities face extra challenges in getting help for opioid problems. This isn't because of their medical condition itself, but because of things like difficulty getting to appointments, lack of understanding from doctors, and prejudice.

Strengths and Limitations

The study used a lot of health records, which is good. However, it couldn't include everyone with a disability, and some things weren't tracked in the records.

Conclusions

People with disabilities need more help getting treatment for opioid problems. Doctors and lawmakers need to work together to make it easier for them to get and stay in treatment.

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Footnotes and Citation

Cite

Thomas, C. P., Stewart, M. T., Ledingham, E., Adams, R. S., Panas, L., & Reif, S. (2023). Quality of opioid use disorder treatment for persons with and without disabling conditions. JAMA network open, 6(3), e232052-e232052.

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