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Medications for opioid use disorder during incarceration and post-release outcomes
Providing medication for opioid use disorder to incarcerated people increases their engagement in community treatment and lowers post-release overdose risk.
Quality of Opioid Use Disorder Treatment for Persons With and Without Disabling Conditions
Adults with disabilities and opioid use disorder are less likely to start and continue medication for opioid use disorder than those without disabilities. People with disabilities face more barriers to treatment.
Association Between Stimulant Treatment and Substance Use Through Adolescence Into Early Adulthood
Stimulant medication for childhood ADHD did not increase or decrease risk for substance use or substance use disorder in adulthood. This finding holds true even after considering age and other factors.
Prevalence of Attention Deficit Hyperactivity Disorder (ADHD) among Substance Use Disorder (SUD) Populations: Meta-Analysis
A new meta-analysis found a high prevalence of ADHD in adults with substance use disorder (SUD). This highlights the need for routine ADHD screening for SUD patients, which could improve treatment strategies.
Brain Networks and Adolescent Alcohol Use
This study identifies brain networks linked to adolescent alcohol use. It found specific networks predict current and future alcohol use risk, with differences noted between sexes.
A brief review of the relationship between addiction and memory systems
Drug addiction alters brain memory systems, particularly in the hippocampus, dorsal striatum, and amygdala. These changes influence how drug-related cues trigger addictive behaviors, shifting from initial impulsive use to compulsive abuse.
A meta‐analysis of the neural substrates of monetary reward anticipation and outcome in Alcohol Use Disorder
Research explores how alcohol use disorder (AUD) affects brain responses to non-alcohol rewards, such as money. Studies show mixed results regarding brain activity during reward anticipation and outcome in individuals with AUD.
Abstinence from Escalation of Cocaine Intake Changes the microRNA Landscape in the Cortico-Accumbal Pathway
Researchers found specific changes in brain microRNA expression in rats after cocaine withdrawal. These changes, particularly in reward and control regions, may reveal new targets for treating cocaine use disorder.
Advancing the preclinical study of comorbid neuroHIV and substance use disorders: Current perspectives and future directions
Substance use disorders increase HIV infection rates and complicate treatment. Animal models are crucial for understanding the disease's impact on the brain and developing new treatments.
Alterations in BNST Intrinsic Functional Connectivity in Early Abstinence from Alcohol Use Disorder
The article finds that changes in brain regions, particularly the BNST network, contribute to relapse in alcohol use disorder. Understanding these changes could help identify individuals at risk and guide new treatments.
Characteristics of Stress Sensitivity in Heroin Use Disorder Patients during Their Opioid Agonist Treatment
Opioid use disorder is a chronic brain disease causing lasting brain changes. This article suggests addiction has a specific psychopathology, distinct from other mental health conditions, that can inform personalized treatment approaches.
Contextual Processing and its Alterations in Patients with Addictive Disorders
Opioid addiction is a major public health issue linked to impaired contextual processing, which impacts decision-making. Researchers are studying how this impairment affects individuals with opioid, alcohol, or both dependencies.
Crosstalk between Mu-Opioid receptors and neuroinflammation: Consequences for drug addiction and pain
This article explains that Mu-Opioid Receptors (MORs) are critical for processes like pain and reward. Dysregulation can lead to disorders like addiction and pain. MORs also influence neuroinflammation, which could lead to new treatments.
Dysregulation of the Endogenous Cannabinoid System Following Opioid Exposure
This review summarizes evidence for endocannabinoid system (ECS) dysregulation in opioid use disorder (OUD). It explores how the ECS, a stress regulatory system, could be a new target for OUD treatments.
GABAergic signaling in alcohol use disorder and withdrawal: Pathological involvement and therapeutic potential
Alcohol use disorders affect many people globally and are linked to numerous health issues. While ethanol impacts various brain pathways, a key focus is its effect on the brain's inhibitory GABA pathway.