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Brief of the Am. Pub. Health Ass’n and the Nat’l Ass’n of Cnty. & City Health Officials as Amici Curiae in Support of Appellees

The brief argues that pharmacies created an ongoing public health nuisance by over-dispensing opioids, causing lasting harm. It seeks court-ordered abatement to fund treatment and recovery services in affected communities.

Opioid epidemicpublic nuisancepharmacies over-dispensingabatement remedyaddiction treatmentoverdose deathsprescription opioidsrecovery services
(2023)

Brief of N.Y. Soc’y of Addiction Med., et al., as Amici Curiae in Support of Appellant

This brief argues that Cameron Douglas's additional prison sentence for drug possession in jail should be reversed.

Opioid dependencesubstance use treatmentheroinimprisonmentcriminal justice systemdrug distributiondrug possessionrelapsecorrectional facilities
(2023)

Brief of Disability Rts. Tex. & Legal Action Ctr. as Amici Curiae in Support of Appellant

Amici argue Alcohol Use Disorder is a chronic brain disorder, meeting the ADA’s definition of disability. They assert the lower court misapplied the law and should have recognized Mr. Mueck’s need for reasonable accommodation.

Alcohol Use Disorderdisability lawADA Amendments Act reasonable accommodationepisodic disabilitychronic brain disorderemployment discriminationgroup therapyschedule accommodationemployer obligations
(2023)

Brain Networks and Adolescent Alcohol Use

This study identifies brain networks linked to adolescent alcohol use. It found specific networks predict current and future alcohol use risk, with differences noted between sexes.

adolescentteenbrain networksalcohol
(2023)

A brief review of the relationship between addiction and memory systems

Drug addiction alters brain memory systems, particularly in the hippocampus, dorsal striatum, and amygdala. These changes influence how drug-related cues trigger addictive behaviors, shifting from initial impulsive use to compulsive abuse.

drug usedrug addictionlearningmemorymemory systemsreturn to userelapse
(2023)

A meta‐analysis of the neural substrates of monetary reward anticipation and outcome in Alcohol Use Disorder

Research explores how alcohol use disorder (AUD) affects brain responses to non-alcohol rewards, such as money. Studies show mixed results regarding brain activity during reward anticipation and outcome in individuals with AUD.

alcohol use disorderfunctional magnetic resonance imagingmeta-analysisfMRImonetary incentive delay taskneuroimagingrewardstriatum
(2023)

Abstinence from Escalation of Cocaine Intake Changes the microRNA Landscape in the Cortico-Accumbal Pathway

Researchers found specific changes in brain microRNA expression in rats after cocaine withdrawal. These changes, particularly in reward and control regions, may reveal new targets for treating cocaine use disorder.

protracted abstinenceprefrontal cortexnucleus accumbensrat brain miRNAsmall RNA sequencingaddiction index
(2023)

Advancing the preclinical study of comorbid neuroHIV and substance use disorders: Current perspectives and future directions

Substance use disorders increase HIV infection rates and complicate treatment. Animal models are crucial for understanding the disease's impact on the brain and developing new treatments.

HIVaddictionpreclinical modelscomorbiditytechniques
(2023)

Alterations in BNST Intrinsic Functional Connectivity in Early Abstinence from Alcohol Use Disorder

The article finds that changes in brain regions, particularly the BNST network, contribute to relapse in alcohol use disorder. Understanding these changes could help identify individuals at risk and guide new treatments.

(2023)

Characteristics of Stress Sensitivity in Heroin Use Disorder Patients during Their Opioid Agonist Treatment

Opioid use disorder is a chronic brain disease causing lasting brain changes. This article suggests addiction has a specific psychopathology, distinct from other mental health conditions, that can inform personalized treatment approaches.

stress sensitivityheroin addictionOATheroin addiction historypsychopathologybehavioural covariates of heroincocaine and cannabis cravingsubjective wellness
(2023)

Contextual Processing and its Alterations in Patients with Addictive Disorders

Opioid addiction is a major public health issue linked to impaired contextual processing, which impacts decision-making. Researchers are studying how this impairment affects individuals with opioid, alcohol, or both dependencies.

heroinalcoholsucroserewardaversionmotivationbeautymonetaryfree willreinforcement
(2023)

Crosstalk between Mu-Opioid receptors and neuroinflammation: Consequences for drug addiction and pain

This article explains that Mu-Opioid Receptors (MORs) are critical for processes like pain and reward. Dysregulation can lead to disorders like addiction and pain. MORs also influence neuroinflammation, which could lead to new treatments.

Opioid signalingNeuroimmunityReinforcementNociception
(2023)

Dysregulation of the Endogenous Cannabinoid System Following Opioid Exposure

This review summarizes evidence for endocannabinoid system (ECS) dysregulation in opioid use disorder (OUD). It explores how the ECS, a stress regulatory system, could be a new target for OUD treatments.

Opioid Use DisorderOpioidsEndocannabinoidsEndocannabinoid systemPharmacologic ActionsAnimal ModelsAddiction
(2023)

GABAergic signaling in alcohol use disorder and withdrawal: Pathological involvement and therapeutic potential

Alcohol use disorders affect many people globally and are linked to numerous health issues. While ethanol impacts various brain pathways, a key focus is its effect on the brain's inhibitory GABA pathway.

alcohol use disordersclinical trialsGABAintegrative approachinterventionspharmacotherapytranslationalunmet need
(2023)

Investigating Behavioral and Neuronal Changes in Adolescent Mice Following Prenatal Exposure to Electronic Cigarette (E-Cigarette) Vapor Containing Nicotine

E-cigarette exposure during the first trimester of mouse pregnancy led to adolescent offspring having altered anxiety, recognition memory, and increased nicotine preference. These changes suggest a link to psychiatric disorder phenotypes.

electronic cigarettesnicotine addictionadolescence
(2023)
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