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Side-effects of MDMA-assisted psychotherapy: A systematic review and meta-analysis

MDMA-assisted psychotherapy appears safe and well-tolerated across various psychiatric conditions. However, reporting of side effects in some studies could be improved.

MDMA-Assisted PsychotherapySystematic ReviewMeta-AnalysisAdverse EventsSide Effects
(2024)

Bad habits–good goals? Meta-analysis and translation of the habit construct to alcoholism

Addiction is often linked to "bad" habits. The article reviews habit and goal-directed behavior in alcohol use disorder, noting that both are part of complex decision-making.

Alcohol Use DisorderHabitual BehaviorNeurobiologyDecision-MakingCompulsivity
(2024)

The impact of civil commitment laws for substance use disorder on opioid overdose deaths

Opioid use and overdose deaths have significantly risen, leading 34 states and D.C. to adopt civil commitment laws for substance use disorder (SUD). These laws allow courts to mandate SUD treatment for individuals meeting specific criteria.

civil commitmentCOVID-19 pandemicopioid use disorder (OUD)substance usage disorders (SUDs)involuntary commitment
(2024)

Views and experiences of involuntary civil commitment of people who use drugs in Massachusetts (Section 35)

Involuntary civil commitment for substance use treatment is used in 38 U.S. states and D.C., including Massachusetts. Research on its effectiveness and potential for harm is mixed.

Involuntary Civil CommitmentSection 35Opioid UseCriminalizationPolicy
(2024)

Investigating the neurobiology of maternal Opioid Use Disorder and prenatal opioid exposure using brain organoid technology

Opioids remain a major global health concern, particularly for pregnant women. Rising opioid use disorder and related treatments in mothers highlight the urgent need to understand opioids' impact on the developing brain.

brain organoidsbrain spheroidsinduced pluripotent stem cellsopioid use disorderopioidsprenatal opioid exposure
(2024)

Advances in the characterization of negative affect caused by acute and protracted opioid withdrawal using animal models

Opioid use disorders are chronic brain disorders with three stages: intoxication, withdrawal, and preoccupation. Negative affective symptoms during withdrawal are a major cause of relapse, suggesting a need for better treatments.

opioid useopioidwithdrawalanimal models
(2023)

Criminal reactions to drug-using offenders: A systematic review of the effect of treatment and/or punishment on reduction of drug use and/or criminal recidivism

Traditional policies to combat psychoactive substance use have increased violence and prison overcrowding.

recidivismdrugstreatmentincarcerationoffenders
(2023)

Examining Sanction Type and Drug Offender Recidivism: A Register-Based Study in Finland

Incarceration in the United States often fails to reduce reoffending, and may even increase it. Poor prison conditions and lack of rehabilitation programming may contribute to this ineffectiveness.

Drug offendersRecidivismFinlandDeterrenceIncarcerationCorrections
(2023)

Assessing Post-Sentencing and Reoffense Outcomes: A Quantitative Study of a Drug Treatment Court In a Western Canadian City

A study found that a Drug Treatment Court in a Western Canadian city significantly lowered reoffense rates. Participants showed better treatment completion, substance use patterns, and social reintegration than a comparison group.

Drug Treatment Courtsubstance use disorderspost-sentencing outcomes
(2023)

Addiction and autonomy: Why emotional dysregulation in addiction impairs autonomy and why it matters

This article discusses how addiction impacts a person’s ability to act autonomously and their moral responsibility. It highlights the often-overlooked role of emotional dysregulation in understanding impaired autonomy in addiction.

addictionautonomyvalueself-controlemotional dysregulationmotivationdecision- making capacitydrug usemoral responsibilityphilosophical debate
(2023)

Efficacy of Cognitive Behavioral Therapy for alcohol and other drug use disorders: Is a one-size-fits-all approach appropriate?

Cognitive Behavioral Therapy (CBT) for alcohol and drug use disorders is a widely studied and used treatment. It helps individuals learn coping skills to change thoughts and behaviors related to substance use.

behavioral treatmentclinical trialsmechanisms of behavior changesubstance use disorder
(2023)

Updated perspectives on the neurobiology of substance use disorders using neuroimaging

Substance use disorders involve brain changes affecting decision-making and reward. Neuroimaging helps understand these alterations, which are influenced by genetics and other factors.

MRIneuroiologysubstance useaddictionneuroimagingAIPETfMRISPECT
(2023)

A comparison of medication-assisted treatment options for opioid addiction: A review of the literature

This literature review investigates medication-assisted treatments for opioid use disorder. It focuses on the efficacy of buprenorphine, methadone, and naltrexone in reducing relapse and harm.

buprenorphineharm reductionMATmedication-assisted treatmentmethadonenaltrexoneopioid addictionopioid use disorderreturn to use reduction
(2023)

Value-based decision-making network functional connectivity correlates with substance use and delay discounting behaviour among young adults

Research aims to find biological markers for substance use disorders. This involves using new dimensional models that combine categories and continuous measures to better understand who might be at risk.

Substance Use DisordersSusceptibility BiomarkersFunctional ConnectivityNeuroimagingFactor Mixture ModellingPreaddiction Delay Discounting Brain NetworksDimensional ModelsHuman Connectome Project
(2023)

Circuit dysfunctions of associative and sensorimotor basal ganglia loops in alcohol use disorder: insights from animal models

Alcohol use disorder (AUD) is linked to brain circuit dysfunction that affects decision-making and action control. Understanding these changes, particularly in the basal ganglia, could help improve AUD therapies.

alcohol use disorderAction ControlBasal GangliaCircuitsSynapses
(2023)
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