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Sexton v. State

The court reversed a sentence reduction denial, finding the judge improperly deferred to the parole board. The judge should have weighed the defendant's youth, addiction, and rehabilitation.

sentence reductionJUVRAparole boardyouthaddictionrehabilitation
(2023)

Neural circuits controlling choice behavior in opioid addiction

Opioid use disorder is a growing epidemic characterized by choosing drugs over natural rewards. Research explores the brain's opioid system and neural circuits to develop new treatments that shift this choice behavior.

Opioid use disorderneural circuitschoice behaviordopamineprefrontal cortexvmPFCNAshellpharmacotherapiesreturn to use
(2023)

Chronic alcohol exposure differentially alters calcium activity of striatal cell populations during actions

Chronic alcohol exposure leads to lasting increases in direct pathway activity but reduces indirect pathway and PV interneuron activity in the brain's decision-making region. This imbalance may contribute to impaired behavioral control.

Dorsal medial striatumAlcoholDecision-makingDirect pathwayIndirect pathway
(2023)

Anticipatory reward dysfunction in alcohol dependence: An electroencephalography monetary incentive delay task study

This study investigated reward processing in alcohol-dependent individuals using EEG.

Event-related potentialsAlcohol dependenceRewardEEGAddictionComputational psychiatry
(2023)

Is Adolescence Believed to be a Period of Greater Risk Taking Than Adulthood?

Adolescents and adults both perceive adolescence as a period of higher risk-taking, especially due to peer presence. This study explores these beliefs using both explicit and implicit measures.

adolescencerisk takingbeliefspeer influenceadulthoodbelief bias
(2023)

Prescription psychostimulants for cocaine use disorder: A review from molecular basis to clinical approach

Cocaine use disorder lacks FDA-approved treatment options. Prescription psychostimulants, which share pharmacological effects with cocaine, show promise in promoting abstinence and reducing drug use.

Cocaine use disorderprescription psychostimulantsamphetaminemethylphenidatemodafinilagonist replacement therapydopamine transporterabstinenceharm reductiontreatment retention
(2023)

Project Harmony: A Meta-Analysis With Individual Patient Data on Behavioral and Pharmacologic Trials for Comorbid Posttraumatic Stress and Alcohol or Other Drug Use Disorders

New research analyzed 36 trials to find the most effective treatments for co-occurring PTSD and substance use disorders. It found various behavioral and pharmacotherapy options, but noted a need for more comparative studies.

Posttraumatic stress disorder (PTSD)substance use disordertrauma-focused therapyalcohol use disorderbehavioral treatmentmeta-analysiscomparative effectivenessintegrated treatment
(2023)

Sex/Gender Differences in the Time-Course for the Development of Substance Use Disorder: A Focus on the Telescoping Effect

Women often experience a faster progression from initial substance use to developing a substance use disorder, known as the "telescoping effect." This pattern is seen with various substances, though some recent studies show inconsistencies.

telescoping effectsubstance use disorderwomenaddictionovarian hormonessex differencesdopamineglutamatemesolimbic pathway
(2023)

Neuroimaging in Adolescents: Post-Traumatic Stress Disorder and Risk for Substance Use Disorders

Adolescents with PTSD have brain changes that may link to developing substance use disorders (SUDs). This review examines neuroimaging studies on this connection and discusses prevention and accurate diagnosis.

adolescenceSUDsPTSDepigeneticsmemoryneuroimagingSUDSubstance Use DisorderLimbic SystemTraumaEpigenetics
(2023)

Neural mechanisms linked to treatment outcomes and recovery in substance-related and addictive disorders

This article reviews brain-based factors tied to recovery from substance use and behavioral addictions. It explores how various treatments, including medication and therapy, relate to brain mechanisms and improved outcomes.

Neurobiologyrecoverysubstance-related disordersgambling disorderinternet gaming disorderimpulsivityaddictive behavioursinternet addictionrecovery processespharmacological treatmentscognitive behavioral therapytreatment outcomes
(2023)

Three decades of research in substance use disorder treatment for syringe services program participants: A scoping review of the literature

Syringe Services Programs reduce disease transmission and connect people who use drugs to medical care. These programs are potential sites to expand substance use disorder treatment, including medication for opioid use disorder.

syringe services programreferral to treatmentpeople who inject drugs
(2023)

Motivated to Compete but Not to Care: The Fundamental Social Motives of Risk-Taking Behaviors

Risk-taking behaviors in adolescents and young adults are often linked to gaining social status and finding mates. These behaviors are more prevalent in young males, aligning with evolutionary drives for reproductive success.

risk-takingteensyoung adultssocial pressurekin caresocial motives
(2023)

Polygenic Risk Scores and Brain Structures Both Contribute to Externalizing Behavior in Childhood: A Study in the Adolescent Brain and Cognitive Development (ABCD) Cohort

Genetic risk for externalizing behaviors in children is associated with differences in brain structure. These brain structures may influence how genetic risks contribute to behavioral issues.

Externalizing behaviorsLate childhoodAdolescenceGray matter volumeWhite matter integrityPolygenic risk scoresMagnetic resonance imagingMRI
(2023)

Put the Juvenile Back in Juvenile Court

Many states determine juvenile court jurisdiction by an offender's age at the time of legal proceedings, not the offense.

rehabilitationjuvenile justiceage of majority
(2023)

Reappraising the Role of Dopamine in Adolescent Risk-Taking Behavior

Dopamine in the brain plays a key role in motivation and reward. Changes in dopamine pathways during adolescence are linked to increased sensation-seeking and risk-taking behaviors.

adolescencedopamineself-regulationimpulsivityrisk-taking
(2023)