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Hippocampal gray matter volume in young adulthood varies with adolescent alcohol use
Adolescent substance use, even at recreational levels, may alter brain structure and cognitive development. Previous research on this link has yielded inconsistent results, highlighting the need for more studies on long-term use patterns.
Abnormal developmental of structural covariance networks in young adults with heavy cannabis use: a 3-year follow-up study
Heavy cannabis use in young adults is linked to structural brain changes, affecting mental health and memory. Research using structural brain networks explores these developmental alterations over time.
Atypical effective connectivity from the frontal cortex to striatum in alcohol use disorder
This study investigates brain alterations in alcohol use disorder (AUD) using brain imaging. It finds specific brain regions contribute to classifying individuals with AUD from healthy controls.
Prefrontal electrophysiological biomarkers and mechanism-based drug effects in a rat model of alcohol addiction
Alcohol use disorder treatment outcomes vary, prompting a search for biomarkers. This study found that certain brain activity patterns, disturbed in individuals with AUD, could predict relapse risk and treatment success.
How should harm reduction be included in care continua for patients with Opioid Use Disorder?
Harm reduction practices aim to reduce negative consequences of substance use, but face barriers like stigma and policy objections. Physicians and policymakers should integrate harm reduction into services and adopt evidence-based policies.
Co-occurring trauma- and stressor-related and substance-related disorders in youth: A narrative review
Many European youth experience trauma and use substances. Trauma increases a young person's risk for substance use problems, including substance use disorder, and both are often underdiagnosed in youth.
Neuroanatomical Variability and Substance Use Initiation in Late Childhood and Early Adolescence
Brain structure differences may be both a cause and consequence of substance use. Smaller global neuroanatomical indices are linked to substance use initiation, even before use begins.
Neurobiology, psychotherapeutic interventions, and emerging therapies in addiction: a systematic review
Addiction involves brain changes affecting reward and control. Therapies like CBT, EMDR, and psychedelics, as well as neurostimulation, can help repair these neural pathways.
The Brain Salience Network at the Intersection of Pain and Substance use Disorders: Insights from Functional Neuroimaging Research
Individuals with substance use disorders exhibit brain changes in their salience network, which handles pain and attention. These alterations are linked to cognitive and behavioral problems.
Structural brain changes associated with cocaine use and digital cognitive behavioral therapy in cocaine use disorder treatment
This study investigates how digital cognitive behavioral therapy (CBT4CBT) and galantamine affect brain structure in individuals with cocaine use disorder. Researchers examined changes in gray matter volume over 12 weeks of treatment.
PrEP facilitators and barriers in substance use bridge clinics for women who engage in sex work and who use drugs
Women who use drugs and engage in sex work face disproportionately high HIV risks, yet PrEP uptake among this group remains very low. Bridge clinics offer a key opportunity to increase PrEP access.
Cannabis cue-reactivity in cannabis use disorder: Diverging evidence in tow distinct cannabis cultures
Cannabis decriminalization affects public attitudes and perceived harm, influencing use and addiction risk. This study explores how differing cannabis policies in Texas and Amsterdam relate to attitudes and brain responses to cannabis cues.
“If you’re strung out and female, they will take advantage of you”: A qualitative study exploring drug use and substance use service experiences among women in Boston and San Francisco
Women face increased drug-related harms and unmet treatment needs. Most substance use services are not designed for women, contributing to a treatment gap.
Does compulsion explain addiction?
This article argues that existing theories inadequately describe human addiction. It finds that obsessive-compulsive disorders differ significantly from addictive behaviors, both in symptoms and neural processes.
Substance use in the correctional settings: A qualitative exploration of individual and contextual characteristics and intervention strategies using the behavior change wheel framework
Substance use in prisons has many influencing factors. Using a behavior change framework, researchers identified intervention strategies and how peer and family engagement can help.