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Relationships between age at first substance use and persistence of cannabis use and cannabis use disorder
Cannabis is the most used illegal drug in Ireland, with increasing addiction and psychiatric problems. Research shows a link between early substance use, especially during adolescence, and later cannabis use disorder.
Clinical impact of COVID-19 on people with substance use disorders
A study found that a small percentage of hospitalized COVID-19 patients had substance use disorders (SUD). Most were middle-aged men with alcohol use disorder and other health conditions; none died.
Early innovations in Opioid Use Disorder treatment and harm reduction during the COVID-19 pandemic: A scoping review
The pandemic worsened overdose deaths and reduced access to opioid use disorder services. Some regulations were relaxed, allowing for expanded telemedicine and take-home medications.
Addressing Racial and Ethnic Disparities In The Use Of Medications For Opioid Use Disorder
The opioid epidemic disproportionately affects people of color, who face significant barriers to accessing effective medication-assisted treatment. These barriers include a lack of providers in their communities and discrimination.
Trauma and Post-Traumatic Stress Disorder in Patients Treated for Opioid Use Disorder: Findings From a 12-Month Cohort Study
This study found that 11% of opioid use disorder patients had PTSD, and nearly half reported past trauma. Those with PTSD were more often female and less likely to be employed or married.
Early Life Stress and Risks for Opioid Misuse: Review of Data Supporting Neurobiological Underpinnings
Early life stress, like abuse or neglect, affects millions of children and increases health risks. This trauma is linked to a higher chance of developing opioid use disorder later in life.
Brief of Amici Curiae Stephen J. Ziegler, Lynn R. Webster, Michael A. Barnes, & the Center for U.S. Policy in Support of Petitioner
The amici argue that prosecuting doctors for medical errors as criminal acts dangerously blurs lines. They contend the government wrongly equates malpractice with criminal intent, harming patient care and physicians.
Psychedelics and Neuroplasticity: A Systematic Review Unraveling the Biological Underpinnings of Psychedelics
Psychedelics like psilocybin and LSD alter mood and cognition by affecting serotonin receptors. These compounds are physiologically safe and induce changes in neuroplasticity, which underlies their lasting psychological effects.
Psychedelics and Other Psychoplastogens for Treating Mental Illness
The article explains that the long-held "chemical imbalance" theory of depression is oversimplified. Instead, depression may stem from issues with brain circuitry, which new "psychoplastogen" treatments could help fix.
Neurotoxicity of methamphetamine: Main effects and mechanisms
Methamphetamine (METH) is a widely abused psychostimulant that can lead to significant health issues. Its use is linked to neurological, psychiatric, and other severe medical complications, including an increased risk of Parkinsonism.
The rise of illicit fentanyls, stimulants and the fourth wave of the opioid overdose crisis
Drug overdose deaths, primarily from synthetic opioids like fentanyl, are a growing crisis. After a temporary decline in 2018, overdose fatalities dramatically increased in 2019 and 2020, with fentanyl driving the surge across the US.
Cannabis use and cannabis use disorder
Cannabis is the third most used controlled substance globally, with 192 million users in 2018. About 1 in 10 regular users develop cannabis use disorder, risking poor mental health.
Interventions for Cannabis Use Disorder
Psychosocial treatments like motivational therapy, cognitive behavioral therapy, and contingency management reduce cannabis use and its severity.
Non-abstinent treatment outcomes for cannabis use disorder
Cannabis Use Disorder is a major public health problem often focused on abstinence in treatment trials. Some studies now explore reducing cannabis use and withdrawal symptoms as alternative treatment goals.
Brain reward circuitry: The overlapping neurobiology of trauma and substance use disorders
Early trauma research linked dissociation to unresolved memories of negative experiences. Decades of study confirm trauma's broad psychological and biological effects, with PTSD symptoms impacting stress response and brain function.