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Juvenile Life Without Parole: Exposing the Parallels Between Juvenile Offenders and Those Who Sentence Them

The US Supreme Court ruled that mandatory life without parole for juveniles is unconstitutional, but a finding of permanent incorrigibility is not required. The US remains the only country to allow juvenile life without parole.

JLWOPjuvenile life without paroleadolescent brain development reduced culpability of juvenilesJones v. Mississippijuvenile justice
(2022)

Factors associated with retention on medications for opioid use disorder among a cohort of adults seeking treatment in the community

People with opioid use disorder who initiated methadone or buprenorphine treatment in the community experienced better retention when they had stable housing and were not using cocaine. Individuals referred from jail had lower retention.

Opioid use disorderMedication-assisted treatmentMOUD retentionMethadoneBuprenorphineHousing statusPain interferenceHIVCocaine useHigh dose MOUD
(2022)

Racial disparities in linkage to care among patients with substance use disorders

Peer support specialists may help link people with substance use disorders to treatment. However, Black patients were less likely to engage in treatment through these specialists in the emergency department.

Peer support specialistsSubstance useRacial disparitiesDiversity and inclusionOpioid use disorderAlcohol use disorderSubstance use disorderAddiction treatmentPublic health
(2022)

Current status of vaccines for substance use disorders: A brief review of human studies

Vaccines for substance use disorders face significant hurdles for human use. While some drug vaccines show promise in animal studies, none have successfully promoted abstinence or reduced drug use in humans.

VaccineAnti-addictionOpiatesNicotineStimulants
(2022)

Longitudinal Analysis of Substance Use Disorder Symptom Severity at Age 18 Years and Substance Use Disorder in Adulthood

Adolescent substance use disorder symptoms are linked to prescription drug use and misuse in adulthood. Those with more severe symptoms as teens face a higher risk of substance use issues later in life.

Substance use disorderadolescenceprescription drug useopioid crisispolysubstance uselongitudinal studyscreening
(2022)

Neural Underpinnings of Social Stress in Substance Use Disorders

Individuals with substance use disorders often use drugs to cope with emotional pain, particularly from chronic social stress. This stress can affect brain responses to drugs and worsen illness risk.

Human drug addictionNeuroimagingSocial stressSubstance use disorderEarly and lifetime adversitytraumareward systembrain connectivityfMRIstress hormones
(2022)

The addiction risk factor: A unitary genetic vulnerability characterizes substance use disorders and their associations with common correlates

Substance use disorders and other mental health conditions share common genetic vulnerabilities. Understanding these genetic links could lead to better prevention and treatment.

Genetics researchBehavioural geneticsAddictionSubstance use disordergenetic liabilitypsychopathologyrisk-takingexecutive functionneuroticismgenome-wide association study (GWAS)genetic correlationpolygenic liability
(2022)

Neuropsychiatric Model of Addiction Simplified

Research shows addiction is a chronic, relapsing brain disorder influenced by both genetics and environment. Early life stress increases substance use risk, but interventions can mitigate these effects.

AddictionAddiction cycleNeurobiologyReinforcementdopaminewithdrawalrelapseneuroplasticitycravingtreatment
(2022)

Persistent and Distressing Psychotic-Like Experiences Using Adolescent Brain Cognitive Development℠ Study Data

Children who experience persistent and distressing psychotic-like experiences show greater impairments across multiple areas.

Childhood psychotic-like experiencesPLEsdistressdevelopmental delaysbrain structure
(2022)

Prosocial Development in Adolescence

Adolescents demonstrated strong adherence to COVID-19 restrictions despite experiencing the most negative effects. Prosocial behavior, which benefits others, is crucial for collective well-being during health crises.

Prosocial behavioradolescencesocial adjustmentsocial brain developmentenvironmental influencesCOVID-19 pandemicCOVID-19
(2022)

Raging Hormones: Why Age-Based Etiological Conceptualizations of the Development of Antisocial Behavior Are Insufficient

Current legal use of neuroscience in courtrooms often overlooks how puberty and hormones influence adolescent antisocial behavior. Greater focus on these factors is needed for accurate legal applications of science.

Developmental neurosciencemodern legal systemantisocial behaviorpubertyhormonesbrain plasticity
(2022)

Risks and Rewards in Adolescent Decision-Making

Adolescence is a time of increased reward-sensitivity and risk-taking. While risk preference can be stable, it changes with age and social context. Self-reports are reliable for measuring risk preference.

Risk takingAdolescentsIndividual differencesSocial influenceInsulaRisk-return
(2022)

Development of Corticostriatal Connectivity Constrains Goal-directed Behavior During Adolescence

This research explores how individuals adjust cognitive effort based on potential rewards. It finds that older participants improve performance in high-stakes situations, a capacity linked to developing brain connections.

Brain development Children Adults GoalsDecision making
(2022)

Stress and Adolescence: Vulnerability and Opportunity During a Sensitive Window of Development

Adolescence is a crucial time when stress can significantly impact brain development and mental health. While it poses heightened risks, this period also offers unique opportunities for resilience and positive recalibration.

adolescencestresssupport
(2022)

The Neurobiology of Antisocial Behavior in Adolescence; Current Knowledge and Relevance for Youth Forensic Clinical Practice

This article reviews the neurobiological factors linked to antisocial behavior in adolescents, including genetic influences and brain differences.

Antisocial behaviorbiopsychosocial approachrisk assessmentneuropsychologyneuroimagingpsychopathic traitsneurobiologyneurodevelopmental problemsadolescence
(2022)