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People v. Smallwood

The court upheld a life sentence for attempted murder. It rejected claims that the sentence was unconstitutional given the defendant's mental illness, substance use, and early trauma.

Eighth Amendmentproportionalityattempted murder life sentencemental illnesssubstance useearly trauma
(2024)

State v. Schober

The West Virginia high court upheld the denial of a probationer's request to use medical cannabis. The court ruled the state's Cannabis Act does not override probation terms or federal law.

medical cannabisprobationmarijuanamarijuana ban
(2024)

United States v. Burchfield

The court ruled a defendant claiming delusions of secret societies was competent to stand trial. This decision followed expert evaluation and testimony.

malingeringsubstance use disordersdelusionssecret societiesspaceships legal competency expert evaluationtestimony
(2024)

United States v. Antonio Taylor

The Sixth Circuit affirmed a conviction, finding a defendant competent despite mental health issues and substance use. The court noted evidence of malingering and a rational understanding of proceedings.

convictioncompetencypersonality disorders alcohol use disordercocaine use disordermalingeringrational understandingclear error
(2024)

DiFraia v. Ransom

DiFraia sued prison officials after being denied opioid-use-disorder medication. The court dismissed individual claims without ruling on substance-use rights.

ADAEighth Amendmentopioid-use-disorder medicationprison officialssubstance-use rightsindividual-capacity claims
(2024)

Cannabis use disorder: From neurobiology to treatment

Cannabis use disorder is a chronic condition affecting millions, especially young adults. The risk of developing CUD increases with the frequency of cannabis use and co-occurs with other mental health conditions.

Cannabis use disorderCUDTHCpsychological interventionspharmacological interventionsCB1 receptorendocannabinoid systemprevalencetreatmentheritability
(2024)

State v. Matrongolo

The court found that drug use could be introduced to question a witness's credibility. This raised due process concerns about addiction's relevance in criminal trials.

drug usewitness credibilityimpeachmentdue processevidentiary questionsaddictionlegal relevancecriminal trials
(2024)

Stress and substance use disorders: Risk, relapse, and treatment outcomes

Stress is a common reason for drug misuse, which can be seen as a coping mechanism. This review introduces an "adaptive stress response" framework and outlines how disruptions in this response contribute to addiction.

addictionsubstance use disorders (SUDs)stress responsecoping mechanismsneurobiological modelsrelapsetreatment failurestress pathophysiologyaddiction risk
(2024)

Harm reduction for Opioid Use Disorder: Strategies and outcome metrics

The opioid crisis has led to over one million overdose deaths. Harm reduction strategies, such as syringe exchange programs, are crucial to mitigate negative consequences and save lives, especially given low treatment initiation rates.

harm reductionoverdose preventionnaloxonesyringe exchangesupervised consumptionsafer supplyfentanyldrug decriminalizationOpioid use disorderoutcome metrics
(2024)

Hippocampal gray matter volume in young adulthood varies with adolescent alcohol use

Adolescent substance use, even at recreational levels, may alter brain structure and cognitive development. Previous research on this link has yielded inconsistent results, highlighting the need for more studies on long-term use patterns.

Adolescent substance usebrain structurealcohol usetobacco usecannabis useneuroimagingcognitive development
(2024)

Abnormal developmental of structural covariance networks in young adults with heavy cannabis use: a 3-year follow-up study

Heavy cannabis use in young adults is linked to structural brain changes, affecting mental health and memory. Research using structural brain networks explores these developmental alterations over time.

Cannabis use disorderbrain developmentneuroimaginglongitudinal study
(2024)

Atypical effective connectivity from the frontal cortex to striatum in alcohol use disorder

This study investigates brain alterations in alcohol use disorder (AUD) using brain imaging. It finds specific brain regions contribute to classifying individuals with AUD from healthy controls.

Alcohol use disorderimpulsivitycompulsivityfMRIresting-state fMRI
(2024)

Prefrontal electrophysiological biomarkers and mechanism-based drug effects in a rat model of alcohol addiction

Alcohol use disorder treatment outcomes vary, prompting a search for biomarkers. This study found that certain brain activity patterns, disturbed in individuals with AUD, could predict relapse risk and treatment success.

Alcohol use disorderElectrophysiological brain activityPsilocybinPrecision medicine
(2024)

How should harm reduction be included in care continua for patients with Opioid Use Disorder?

Harm reduction practices aim to reduce negative consequences of substance use, but face barriers like stigma and policy objections. Physicians and policymakers should integrate harm reduction into services and adopt evidence-based policies.

Harm reductionopioid use disorder (OUD)Medication-assisted treatment (MOUD)naloxonesyringe service programsHousing Firstsocial determinants of health (SDOH)evidence-based practiceshealth equityoverdose prevention
(2024)

Co-occurring trauma- and stressor-related and substance-related disorders in youth: A narrative review

Many European youth experience trauma and use substances. Trauma increases a young person's risk for substance use problems, including substance use disorder, and both are often underdiagnosed in youth.

Adverse childhood eventsPTSDsubstance use disorderstraumaco-occurring disordersadolescentstreatment
(2024)
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