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A Case Report about the Interrelation of Trauma, Emotional and Behavioral Response and Severe Alcohol Use Disorder

This article describes a case study of a male client seeking treatment for anger, violent behavior, and alcohol use. It highlights links between trauma, anger suppression, and substance use, emphasizing culturally informed care.

Alcohol Use DisorderRaceHomosexualityMental Health
(2021)

MDMA-assisted therapy for severe PTSD: a randomized, double-blind, placebo-controlled phase 3 study

MDMA-assisted therapy significantly reduced PTSD symptoms and functional impairment compared to placebo. It was generally well-tolerated, with more adverse events in the MDMA group.

MDMA-Assisted Therapy (MDMA-AT)Post-Traumatic Stress Disorder (PTSD)Randomized Controlled Trial
(2021)

Assessing HIV and Overdose Risks for People Who Use Drugs Exposed to Compulsory Drug Abstinence Programs (CDAP): A Systematic Review and Meta-analysis

Globally, drug use leads to many health problems, including HIV and overdose deaths.

Compulsory drug abstinence programsoverdosemedications for opioid use disorderharm reductioninjection drug usesystematic review
(2021)

Neurobiology of alcohol seeking behavior

Relapse is a major challenge in addiction treatment, with many people experiencing it within three months of abstinence. Researchers use animal models to study relapse triggers like stress, cues, and small alcohol re-exposure.

GABAalcohol seekinganimal modeldopamineglutamateopioid receptorsrelapse
(2021)

Opioid-Induced Structural and Functional Plasticity of Medium-Spiny Neurons in the Nucleus Accumbens

Opioid use disorder is a chronic condition with a high potential for relapse. This is partly due to drug-induced changes in key brain areas that make individuals more susceptible to compulsive use.

AddictionDendritesDendritic spinesHeroinMedium-spiny neuronsMorphineNucleus accumbensOpioid Use DisorderPlasticity
(2021)

Jones v. Armbrister

The court dismissed a patient's claims that denying opioid treatment violated the ADA and state law. No deliberate indifference or discrimination was found.

ADAopioid treatmentdisability discriminationdeliberate indifferenceequal protectionfederal casestate lawdismissed claimscourt decisionmedication denial
(2020)

Meirs v. Ottawa County

The Sixth Circuit affirmed a summary judgment for the jail and medical provider following a detainee's suicide, finding no deliberate indifference or Monell liability.

Sixth Circuitsummary judgmentdetainee suicidedeliberate indifferenceMonell liabilityBatson challengejailmedical providertrial rulingsaffirmed
(2020)

Quintana v. Santa Fe County Board of Commissioners

The court revived claims that an officer ignored a detainee's heroin withdrawal. It also held that the jail's intake failures could lead to liability.

federal casedeliberate indifferenceheroin withdrawalMonell liabilitydetaineeintake failuresjailofficerplaintiffsplausibly alleged
(2020)

Chamberlain v. Virginia Department of Corrections

The court denied an incarcerated man's request for opioid addiction medication. It found he did not prove immediate harm or medical need for the treatment.

Methadonebuprenorphineopioid use disorderMAT (Medication-Assisted Treatment)incarceratedpreliminary injunctionirreparable harmmedical necessityfederal casecourt ruling
(2020)

State v. Stack

The court ruled that voluntary intoxication cannot be used as an insanity defense. This upheld a murder conviction for a man who claimed alcohol caused a blackout during a fatal assault.

alcohol use disorderblackoutnegating intentfatal assaultvoluntary intoxicationinsanitymurder
(2020)

35 faith leaders say blocking Safehouse's overdose-prevention site violates their religious freedom. Their faiths command them to preserve life and show compassion to those in need.

Defendants argue an overdose prevention site would save lives by providing a supervised, hygienic space for drug consumption with immediate medical care and referrals, without violating federal law.

(2020)

Brief of the Society of Cannabis Clinicians, the Association of Cannabis Specialists, the Drug Policy Alliance, and the Americans for Safe Access Foundation as Amici Curiae

This brief argues that a judicial district's policy prohibiting medical marijuana for probationers unlawfully overrides state law. It contends the policy endangers patients by denying physician-approved treatment and lacks scientific basis.

medical marijuanaprobation supervisionPennsylvania lawMedical Marijuana Act52nd Judicial Districtpatient rightsmedical treatmentpolicy conflictDepartment of Health
(2020)

Brain networks underlying vulnerability and resilience to drug addiction

Research suggests that some individuals exhibit resilience to drug addiction, even with regular use or a family history. This resilience may involve compensatory brain systems that buffer the impact of drug use.

functional connectivitycocainevulnerabilityresiliencefMRIaddictionresiliencebrain connectivitystriatal subsystemsdopamine signalingfamilial riskstimulant drugshabit formationgoal-directed behaviorcompulsive behavior
(2020)

Addiction is driven by excessive goal-directed drug choice under negative affect: Translational critique of habit and compulsion theory

This paper evaluates goal-directed choice, habit, and compulsion theories of addiction. It finds that addiction is primarily driven by excessive goal-directed drug choice influenced by negative emotions.

Addictiongoal-directed choicehabitcompulsionnegative affectdrug rewarddecision-makingdependencewithdrawalstress
(2020)

Combined Pharmacotherapy and Cognitive Behavioral Therapy for Adults With Alcohol or Substance Use Disorders - A Systematic Review and Meta-analysis

Combined cognitive behavioral therapy and medication for addiction offered more benefits than usual care and medication alone. This highlights the importance of incorporating evidence-based therapies with pharmacotherapy in treatment.

(2020)
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