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Neural Processes During Adolescent Risky Decision Making Are Associated with Conformity to Peer Influence

Adolescents often take more risks, especially with peers, which can be both harmful and beneficial. This study explores how brain activity and connections relate to risky driving under peer influence.

AdolescentsRisk takingPeer influenceDrivingfMRIBART
(2020)

Mechanisms Linking Childhood Trauma Exposure and Psychopathology: a Transdiagnostic Model of Risk and Resilience

Childhood trauma is a significant risk factor for various mental health conditions throughout life. It influences social, emotional, and biological development, increasing vulnerability to psychopathology.

StressTraumaAdolescentsMental health disordersEmotional controlAging
(2020)

"Permanently Incorrigible" Is a Patently Ineffective Standard: Reforming the Administration of Juvenile Life Without Parole

This article examines challenges in applying the Supreme Court's "irreparable corruption" standard for juvenile life without parole.

juvenile life without paroleJLWOPEighth amendmentMiller v. Alabamapermanent incorrigibilitydiscretionary JLWOP sentencemitigating factorsMontgomery v. LouisianaSixth Amendment
(2020)

Healthy Development as a Human Right: Insights from Developmental Neuroscience for Youth Justice

This article argues that healthy development is a human right, not a privilege. It highlights how the US justice system often denies this right to youth, especially children of color, by treating them as adults.

Brain developmentLawAdolescenceRightsBraincognitiondevelopment
(2020)

Estimating the impact of wide scale uptake of screening and medications for opioid use disorder in US prisons and jails

Implementing medication for opioid use disorder in all US prisons and jails could prevent many overdose deaths. An estimated 3,200 to 11,200 lives could be saved annually if these treatments were widely available.

jailmedications for opioid use disorderopioidsoverdoseprison
(2020)

Alcohol Addiction, Gut Microbiota, and Alcoholism Treatment: A Review

Alcohol use disorder causes significant death and disability, impacting brain function and increasing risks of anxiety, depression, and liver disease. Current treatments offer limited success, highlighting a need for new interventions.

CRISPRalcohol addictionalcohol encephalopathyalcohol liver diseasealcoholism medicationgene editing therapygut microbiotagut–brain axis
(2020)

E-cigarettes, nicotine, the lung and the brain: Multi-level cascading pathophysiology

E-cigarettes are perceived as safer than tobacco, but their health effects, especially on the brain and lungs, are not fully understood. Research is struggling to keep pace with increasing use and changing perceptions.

E-cigarettesnicotinelung diseaseaddictionsmoking cessationbrain
(2020)

Sex Differences in the Neurobiology of Alcohol Use Disorder

This article highlights that sex differences influence alcohol use disorder (AUD) risk. Researchers are increasingly including females in studies to understand how sex impacts the transition from alcohol use to misuse.

adolescencealcoholalcohol use disorderanimal modelsbrainsex differencesstressprefrontal cortexbinge drinkingalcohol withdrawal
(2020)

Insights into the neurobiology of craving in Opioid Use Disorder

Opioid Use Disorder (OUD) is driven by brain changes that enhance drug-related craving. This craving, a complex interplay of reward, stress, and learning, fuels drug-seeking and relapse.

Drug cravingIncentive sensitizationNegative affectNegative reinforcementOpioid Use DisorderStress
(2020)

Methamphetamine Use Disorder: The Next Addiction Crisis

Methamphetamine use and overdose deaths have significantly increased, posing a major public health challenge. The drug's complex neurobiology extends beyond traditional views, affecting multiple biological pathways in the brain.

Methamphetamine use disorderneurobiologytreatmentcognitive impairmentcardiovascular diseasepharmacological interventions
(2020)

Attention-deficit/hyperactivity disorder and lifetime cannabis use: Genetic overlap and causality

The study found a shared genetic basis between ADHD and lifetime cannabis use. This shared genetic background may partially explain why individuals with ADHD have a higher risk of cannabis use.

ADHDcannabis usegenetic correlationsubstance use disorderheritability
(2020)

One is Not Enough: Understanding and Modeling Polysubstance Use

Drug addiction is a widespread and costly public health crisis. Polysubstance use is common and leads to worse treatment outcomes, including higher relapse rates and mortality.

substance useaddictionreward circuitrypreclinical modelsneuronal signaling and behaviorreviewneuorbiology of addictionpolydrug
(2020)

Common and separable neural alterations in substance use disorders: A coordinate-based meta-analyses of functional neuroimaging studies in humans

The article suggests that while addiction shares common brain pathways, different substances may also cause specific brain changes. Understanding these unique alterations could lead to better-targeted addiction treatments.

alcoholcannabiscocainecognitionstriatumfMRInicotinerewardsubstance use disorder
(2020)

Adolescent Brain Development and Progressive Legal Responsibility in the Latin American Context

Neuroscience research highlights the complexity of defining adolescence due to non-uniform brain development. This understanding influences legal systems, particularly in decisions about adolescent criminal responsibility.

Teenage BrainAdolescent lawCriminalAdolescenceBehaviorNeuroscienceNeurolawJuvenile criminal behaviorjuvenile criminal lawadolescent brainlegal responsibility
(2020)

Adolescent Psychopathology: the Role of Brain-based Diatheses, Sensitivities, and Susceptibilities

Some adolescents experience problems while others thrive due to a complex interplay of biology and environment. Brain structure and function influence an individual's vulnerability or susceptibility to their surroundings.

AdolescenceStressBrain developmentImpulsivityRewardsPeer influenceChronic health conditionshealth condition
(2020)
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