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Addressing adolescent substance use with a public health prevention framework: The case for harm reduction

Harm reduction principles should be integrated with traditional prevention for adolescents with problematic substance use. This approach can help minimize negative health and social impacts.

Adolescentsharm reductionsubstance use disorderaddiction
(2022)

Association between contact with mental health and substance use services and reincarceration after release from prison

A study found that people receiving mental health or substance use services after prison release had a lower risk of re-incarceration. However, consistent engagement with these services improved outcomes more.

Recidivismincarcerationmental health servicessubstance use treatmentparoleprison releasecommunity-based servicesre-incarcerationhealth service contactrisk of reoffending
(2022)

PriSUD-Nordic—Diagnosing and Treating Substance Use Disorders in the Prison Population: Protocol for a Mixed Methods Study

This project examines substance use disorders in Nordic prisons across three periods: before, during, and after imprisonment. It combines extensive registry data with qualitative research to understand this vulnerable population.

substance use disordersprisoncriminal justiceepidemiologymixed methodsharm reductiontreatment
(2022)

Perspectives of Adults with Disabilities and Opioid Misuse: Qualitative Findings Illuminating Experiences with Stigma and Substance Use Treatment

Adults with disabilities are more likely to misuse prescription opioids and experience opioid use disorders. They face unique barriers to treatment, including stigma and inaccessible care, compounded by their other identities.

disabilitiesopioidspainmental illnessqualitativebarriers
(2022)

Stimulant use disorder diagnosis and opioid agonist treatment dispensation following release from prison: A cohort study

People released from prison are at high risk for overdose. This study found that a history of stimulant use disorder reduced the likelihood of receiving critical opioid addiction treatment within two days of release in British Columbia.

Stimulant use disorderOpioid use disorderOpioid agonist treatmentIncarcerationPrisonMental healthPolysubstance use
(2022)

Neural substrates of substance use disorders

Subcortical disease and lack of prefrontal control are common findings in neuroimaging studies of substance use. It is still unclear if these are pre-existing traits or consequences of substance use.

addictioncontrolneuroimagingprefrontalsaliencestriatumsubstance use disorder
(2022)

Structural and functional brain recovery in individuals with substance use disorders during abstinence: A review of longitudinal neuroimaging studies

This review focuses on longitudinal neuroimaging studies to understand how the brain changes during abstinence from substance use. It aims to identify mechanisms associated with sustained abstinence or relapse.

AbstinenceAddictionAlcoholCocaineLongitudinalNeuroimagingRecoverySubstance use disordersSUD
(2022)

Impact of Substance Use Disorder on Between-Network Brain Connectivity in Early Psychosis

Psychotic disorders involve brain network dysconnectivity, with abnormalities in salience, default mode, and central executive networks. Substance use may worsen these connectivity issues and influence symptom severity.

Triple Network Modelbetween-network connectivityfunctional connectivitypsychosisresting state networkssubstance use disorderSUD
(2022)

Advances in neuroimaging studies of Alcohol Use Disorder (AUD)

Neuroimaging reveals alcohol use disorder (AUD) patients experience reduced gray matter volume, especially in frontal brain regions, and significant white matter changes. Abstinence can partially reverse these brain deficits.

alcohol use disorderelectroencephalographyfunctional magnetic resonance imagingprefrontal cortexstructural magnetic resonance imagingtranscranial magnetic stimulation
(2022)

Pharmacological, neural, and psychological mechanisms underlying psychedelics: A critical review

Psychedelic drugs show promise for treating mental disorders, including depression and addiction. Research is exploring how these substances affect the brain and mind at different levels to understand their therapeutic potential.

Psychedelics5-HT2A receptorLevels of explanationPharmacologyNeurosciencePsychology
(2022)

Psychedelics and health behaviour change

Psychedelic compounds are being explored as tools to promote healthier lifestyles and treat various conditions. Research from past decades and renewed 21st-century studies show promising results for treating mood disorders and addictions.

PsychedelicsHealth behavior changeAddictionPsilocybinPsychedelic therapyMental healthSelf-determinationNeuroplasticityCognitive Behavioral TherapyWellness
(2022)

Adverse effects of psychedelics: From anecdotes and misinformation to systematic science

Psychedelic medicines are gaining attention for medical use, leading to regulatory changes in the US and Canada. This review examines potential risks, aiming to distinguish facts from misinformation.

PsychedelicsLSDpsilocybinmescalineDMTayahuascaadverse effectshallucinogen persisting perception disorderpsychedelic-assisted psychotherapyneurotoxicity
(2022)

Associations between cannabis use, Cannabis Use Disorder, and mood disorders: Longitudinal, genetic, and neurocognitive evidence

Cannabis use is widespread, and rates of use in individuals with depression are increasing faster than in non-depressed individuals. Many report using cannabis to alleviate mood disorder symptoms, but it can also worsen them.

Biploar disorderCannabis useCannabis use disorderDepressionMood disordersSuicide
(2022)

Synaptic changes induced by cannabinoid drugs and Cannabis Use Disorder

Cannabis use is widespread and increasingly popular, despite risks like dependence and withdrawal. While behavioral effects are known, the underlying neurobiological mechanisms are still being explored.

Cannabinoid 1 receptorCannabis sativaDelta-9 tetrahydrocannabinolEndocannabinoidLong-term depressionLong-term potentiationSynaptic Modulation
(2022)

Thalamocortical functional connectivity and cannabis use in men with childhood Attention-Deficit/Hyperactivity Disorder

ADHD symptoms often persist into adulthood, increasing the risk of substance use disorder, including cannabis use. Brain regions like the thalamus may play a role in this increased risk.

cannabisADHD (Attention-Deficit/Hyperactivity Disorder)Substance Use DisorderfMRI
(2022)