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Proposed Brief of Amici Curiae Drug Policy Alliance et al. in Support of Appellant’s Motion for Leave to Appeal to the Court of Appeals

This brief argues a father cannot be found negligent for his pregnant partner's drug use. Medical experts oppose punitive actions during pregnancy, citing harm to women, children, and families.

Child neglectsubstance usepregnancyfamily separationmaternal and fetal healthopioid use disorderracial disparitiesfoster care
(2025)

N-acetylcysteine for youth cannabis use disorder: Randomized controlled trial main findings

A study found N-acetylcysteine, an over-the-counter supplement, helped young people aged 14–21 reduce cannabis use when combined with brief counseling. This effect was not observed in adults.

Cannabis use disorder N-acetylcysteineYouthAdolescent cannabis useClinical trialContingency management
(2025)

Developmental differences in social information use under uncertainty: A neurocomputational approach

Adolescents are more influenced by peers due to increased uncertainty in new situations. They learn to weigh peer information based on their own knowledge and the peer's perceived expertise.

DevelopmentAdolescenceSocial learningUncertaintydecision-makingNeuroimagingMetacognition
(2025)

"Sex-specific differences in brain activity dynamics of youth with a family history of substance use disorder "

A family history of substance use disorder (SUD) and an individual's sex influence their vulnerability to SUD.

(2025)

From relaxed beliefs under psychedelics (REBUS) to revised beliefs after psychedelics (REBAS)

The study found that psilocybin reduced confidence in negative self-beliefs, both immediately and weeks later. This suggests psychedelics could help revise unhelpful thought patterns and improve well-being.

Psychedelic therapyREBUS modelneural entropypsilocybinwell-being
(2025)

Neurobiological intersections of stress and substance use disorders

Substance Use Disorders (SUDs) are brain diseases characterized by compulsive drug seeking despite negative consequences. Stress significantly contributes to SUD development and relapse by impacting brain reward and stress systems.

HPA axisneuroinflammationearly life stressmood disorderssubstance use disorder
(2025)

Efficacy and Clinical Application of Physical Activity in Substance Use Disorder Rehabilitation: A Review on Mechanism and Benefits

Physical activity (PA) offers a comprehensive approach to treating substance use disorders (SUDs) by enhancing brain function, reducing cravings, and improving mood. Regular PA supports long-term recovery and overall well-being.

substance use disordersphysical activityrelapse preventioncraving reductionmental healthrehabilitation
(2025)

The role of personality functioning and childhood trauma in patients in opioid substitution treatment

The study found that individuals with opioid use disorders in a substitution program have significant impairments in personality functioning, which are linked to childhood trauma and injecting drug use.

personality functioningsubstance use disordersopioid use disordersinjecting drug usechildhood trauma
(2025)

Novel Insights into Addiction Management: A Meta-Analysis on Intervention for Relapse Prevention

Addiction is a chronic brain disorder, and relapse rates for substance use remain high after treatment. This analysis explores recent developments in preventing relapse from alcohol and drug addiction.

addictionrelapse preventionpharmacological interventionnon-pharmacological interventiondetoxification
(2025)

Exploration of Effective Substance Use Relapse Prevention Programmes for the Youth: An Integrative Literature Review

Many young people with substance use disorders relapse after treatment. Effective relapse prevention programs, considering social and cultural factors, are crucial for supporting long-term recovery in youth.

check-upspreventionprogrammerelapsesubstance use
(2025)

MDMA and MDMA-Assisted Therapy

Studies show MDMA-Assisted Therapy effectively treats PTSD, but the FDA requires further research before approval. It's crucial to distinguish between clinical MDMA therapy and recreational MDMA use.

MDMAMDMA-Assisted TherapyPosttraumatic Stress Disorder (PTSD)Mental Health Treatment
(2025)

What’s Old Is New Again in Addiction Treatment: The Expansion of Involuntary Commitment in the United States

A recent report found that people involuntarily committed for substance use disorder in Massachusetts faced a 1.4-fold increased risk of non-fatal overdose after release, and potentially higher risk of death.

Involuntary commitmentsubstance use disorderaddiction treatmenttreatment outcomesevidence-based treatmentmortality risk
(2025)

Expanding Access to Medications for Opioid Use Disorder in the Criminal Legal System Beyond Prisons and Jails

The criminal justice system worsens the overdose crisis by denying access to life-saving medications for opioid use disorder (MOUD). MOUD is basic healthcare and proven to reduce deaths, but it is often banned in legal settings.

MOUDOpioid Use DisorderCriminal Justice SystemOverdose CrisisAmericans with Disabilities Act (ADA)ProbationParoleIncarcerationSubstance Use Disorder
(2025)

The Changing Approach to Addiction - From Incarceration to Treatment and Recovery Support

"Tough-on-crime" drug policies have been ineffective. Integrating clinical care with long-term community-based support services and peer recovery efforts improves outcomes, shortens recovery time, and offers significant cost savings.

Substance Use Disorderaddiction treatmentrecovery support servicesclinic-community integration long-term recoveryevidence-based treatmentsdrug policy reformopioid use disorderpeer supportcriminalization of drug use
(2025)

Bridging the gap: Post-release outcome evaluation of the first jail-based telemedicine buprenorphine program

Recently released incarcerated individuals face a significantly higher risk of overdose death. Providing medication-assisted treatment (MAT) for opioid use disorder during and after incarceration can reduce overdose deaths and relapse.

Opioid Use Disorder (OUD)Medications for Opioid Use Disorder (MOUD)BuprenorphineTelemedicineCarceral settingsIncarcerated individualsRural areasOverdose preventionTreatment engagementPost-release outcomes
(2025)