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United States v. Shangreaux
The court denied compassionate release, ruling that COVID-19 and stimulant use disorder were not extraordinary circumstances. Release was also opposed by sentencing factors.
Drug addiction: From bench to bedside
Drug addiction causes 11.8 million deaths annually, surpassing cancer deaths. It is a chronic, relapsing brain disease shaped by biological, behavioral, and social factors. Effective treatment requires a personalized approach.
Gray and white matter morphology in substance use disorders: A neuroimaging systematic review and meta-analysis
Substance use disorders (SUDs) are a major public health issue affecting millions worldwide. SUDs cause brain changes that can be observed with MRI, but the specific regions affected vary by substance and individual.
Substance Use Disorders and Behavioral Addictions During the COVID-19 Pandemic and COVID-19-Related Restrictions
The COVID-19 pandemic and associated restrictions have negatively impacted mental health across the U.S.
Association of substance use disorders and drug overdose with adverse COVID-19 outcomes in New York City: January–October 2020
People with substance use disorders (SUDs) and a history of overdose face a higher risk of severe COVID-19 outcomes, including hospitalization, ICU admission, and death.
COVID-19 and substance use in adolescents
The COVID-19 pandemic's impact on adolescent substance use is unclear due to inconsistent study results. While stress and isolation are risk factors, stay-at-home orders might also reduce access to substances.
Use of Medications for Alcohol Use Disorder in the US: Results From the 2019 National Survey on Drug Use and Health
Only 1.6% of adults with past-year alcohol use disorder (AUD) used medication for AUD (MAUD). Those using MAUD were more likely to live in large cities, have frequent emergency room visits, and receive mental health care.
Racial/ethnic equity in substance use treatment research: The way forward
Opioid and substance use disorder treatment outcomes are worse for racial and ethnic minorities. Research should focus on recruiting sufficient minority participants and conducting valid analyses to reduce these disparities.
Disparities in Opioid Overdose Death Trends by Race/Ethnicity, 2018–2019, From the HEALing Communities Study
Opioid overdose deaths remained steady overall in 2018-2019, but non-Hispanic Black individuals saw a 38% increase. This growing disparity was most significant in Kentucky and Ohio.
Examining barriers to harm reduction and child welfare services for pregnant women and mothers who use substances using a stigma action framework
This paper identifies how multiple levels of stigma create barriers for pregnant women and mothers using substances, especially those in child welfare services. It offers evidence-based solutions to address these systemic issues.
Lost in Translation: The Gap Between Neurobiological Mechanisms and Psychosocial Treatment Research for Substance Use Disorders
Substance use disorders involve brain changes that drive continued use despite harm. Current treatments have limited success, with many individuals relapsing within a year.
Promising vulnerability markers of substance use and misuse: A review of human neurobehavioral studies
Adolescence is a key period for substance use onset and escalation. This review examines neurobehavioral markers, including brain structure, function, and cognitive measures, that predict early and worsening substance use.
Investigating Patients' Perceptions of Residential Substance Use Treatment: Is Drop Out a Deliberate or Impulsive Act?
Dropping out of residential substance use disorder treatment is a complex issue with serious consequences. Research suggests focusing on patient needs, satisfaction, and staff competence may reduce dropout rates.
The convergent neuroscience of affective pain and substance use disorder
This article explores how the desire for pain relief can contribute to substance use disorders. It highlights that both opioids and alcohol are sought to alleviate pain and negative emotions, despite risks associated with their misuse.
Alcohol and Cannabis Use and the Developing Brain
Adolescence involves significant brain changes until about age 25. Alcohol and cannabis use during this period can negatively affect brain development and increase vulnerability to substance use disorders.