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Extended-Release vs Sublingual Buprenorphine in Pregnancy Through 12 Months Post Partum A Randomized Clinical Trial

A clinical trial found extended-release buprenorphine to be as effective and safe as sublingual buprenorphine for treating opioid use disorder in pregnant people. This extended-release option helps improve adherence and reduce misuse risks.

buprenorphineextended-releaseopioid use disorderpregnancyneonatal opioid withdrawal syndrome
(2026)

Long-term relapse: markers, mechanisms, and implications for disease management in alcohol use disorder

Research on alcohol use disorder often focuses on short-term relapse. However, factors influencing long-term relapse after sustained remission are largely unknown, despite its importance for ongoing recovery.

Alcohol Use Disorder (AUD)long-term relapse (LTR)sustained remissionrelapse preventionrecoverybio-psycho-social factorsrecovery support services (RSS)risk factorscognitive vigilancemental health symptoms
(2026)

Culture, Trauma, and Memory in Investigative Interviews

This article examines how cultural differences and trauma affect memory, disclosure, and communication in cross-cultural investigative interviews. It offers guidance for interviewers, aiming to improve rapport-based interviewing.

Cultural differencescross-cultural communicationtraumatic memoriesinvestigative interviewingeyewitness memory
(2026)

Developing a strong sense of coherence as a pathway beyond intergenerational trauma: Narratives of adult children of Vietnamese boat refugees

This study found that adult children of Vietnamese boat refugees can recover from intergenerational trauma. They achieve this through culturally responsive care, finding meaning in their past, and separating from unhealthy family patterns.

intergenerational traumaVietnamese boat refugeeschildren of refugeessense of coherencedifferentiation of selfsalutogenesisfamily systems theory
(2026)

The relationship between childhood trauma, personality, and subjective well-being in early and late adolescence: a network analysis

Childhood trauma significantly predicts lower subjective well-being in adolescents. Trauma hinders positive personality development and fosters negative traits, which in turn reduces well-being.

Subjective well-beingchildhood traumapersonality traitsadolescenceneuroticismself-esteememotional abuseemotional neglectnetwork analysisdevelopmental stages
(2026)

Pre-Arrest Diversion-To-Treatment for Adults with Substance Use Disorder: Health Outcomes and Predictors of Program Completion

Pre-arrest diversion programs offer an alternative to incarceration for drug-related crimes. These programs show promise in reducing re-arrests and improving health outcomes like overdose rates among participants.

pre-arrest diversioncrimesubstance use disorderopioid use disorderaddictiontreatment
(2025)

Medication for opioid use disorder service delivery in carceral facilities: Update and summary report

Incarceration increases the risk of opioid overdose upon release due to decreased drug tolerance. Providing medication for opioid use disorder during incarceration significantly reduces overdose deaths.

overdosecriminal legal systemMedication-assisted treatment (MAT)MOUDincarcerationBuprenorphineMethadoneNaltrexoneOpioid use disorder (OUD)Recidivism
(2025)

Early Life Stress and Substance Use Disorders: Underlying Neurobiology and Pathways to Adverse Outcomes

Early life stress is a major public health concern impacting over half of adults. It significantly increases the risk for substance use disorders and other mental and physical illnesses, reducing lifespan.

Early Life StressSubstance Use DisordersAddictionNeurobiologyHPA AxisRelapsePrefrontal CortexImpulsivityComorbid Psychopathology
(2025)

Reward neurocircuitry predicts longitudinal changes in alcohol use following trauma exposure

This study explored how brain responses to reward in recently traumatized individuals predict changes in alcohol use. It also examined how these brain differences might vary between sexes.

AlcoholFunctional ConnectivityNeuroimagingRewardTraumaVentral tegmental area
(2025)

Common neural patterns of substance use disorder: A seed-based resting-state functional connectivity meta-analysis

Substance use disorder (SUD) involves complex brain changes. Research identifies consistent functional connectivity abnormalities in brain reward circuits across different substances and addiction stages, linking these to impulsivity.

Substance use disorderresting-state fMRIreward circuitryfunctional connectivityimpulsivity meta-analysis
(2025)

Prevalence of adverse childhood experiences among individuals in treatment for substance use disorder: Are ACE associated differently across type of abuse and quantity of consumption?

Adverse Childhood Experiences (ACE) are linked to many adult health issues. Studies find Indigenous populations, including those in Greenland, experience more ACE and are more likely to develop substance use disorders.

GreenlandAdverse Childhood Experiences (ACE)ArcticAlcohol useCannabis useSubstance use treatmentSubstance use Disorderparental substance use
(2025)

Recovery housing for substance use disorder: A systematic review

Substance use disorder (SUD) is a major global public health problem. Recovery housing offers vital long-term support, significantly improving recovery outcomes and cost-effectiveness for those seeking remission.

recovery housingrecovery residenceOxford housesober homesystematic reviewsubstance useopioid usealcohol use
(2025)

Redefining low-threshold buprenorphine access in an integrated mobile clinic program: Factors associated with treatment retention

A mobile clinic in Baltimore City expanded its low-barrier buprenorphine program by increasing time between visits and drug testing. These changes aimed to further reduce barriers to care for people who use drugs or experience homelessness.

buprenorphinemobilelow-thresholdbuprenorphine doseretention
(2025)

Unravelling Polygenic risk and Environmental Interactions in Adolescent Polysubstance Use: a US Population-Based Observational Study

This study explores how genetic risks and environmental factors interact to influence adolescent polysubstance use. Findings aim to reveal underlying mechanisms and inform prevention strategies for substance use disorders.

Polysubstance usepolygenic scoresenvironmental factorsadolescents
(2025)

Drug Addiction and Incarceration: A Call for Research and Transparency Among Prison-Based Substance Abuse Treatment programs

A significant majority of incarcerated individuals in the U.S. have a history of illicit drug use, and over half have diagnosable addictions. This highlights an urgent need for effective, transparent prison-based treatment programs.

recidivismdrug addictionCBTcontingency managementtherapeutic communitiespharmacological treatmenttwelve-step programsabstinencePrison-based substance use treatment programs
(2025)
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