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Organic Cannabis v. Comm'r of Internal Revenue

The Ninth Circuit ruled that medical cannabis dispensaries filed their Tax Court petitions too late. The IRS mailer was valid, so the case was dismissed.

medical cannabis dispensariesIRS mailertimely filingdismissal
(2020)

Health outcomes and cost-effectiveness of diversion programs for low-level drug offenders: A model-based analysis

A jail diversion program for drug offenses would reduce HIV and HCV infections, overdose deaths, and incarceration rates while also saving money. Such programs benefit both individuals and the community.

Jail diversion programsoverdoseincarcerationrecidivismdrug courtscost-effectiveness
(2020)

Individual Differences in Accumbofrontal Tract Integrity Relate to Risky Decisions Under Stress in Adolescents and Adults

Adolescents' individual brain development and exposure to stress may influence their risk-taking decisions. A specific brain pathway, the accumbofrontal tract, can differentiate how stress affects risky decisions, regardless of age.

StressDecision-makingDTIAdolescenceAccumbofrontalDiffusion tensor imaging
(2020)

Initiating Pharmacologic Treatment in Tobacco-Dependent Adults. An Official American Thoracic Society Clinical Practice Guideline

Tobacco dependence is a chronic addiction that requires sustained treatment, not just encouragement to quit. New guidelines offer an evidence-based pathway for initial medication therapy to improve patient care.

dependencesmokingtobaccotreatmentpharmacotherapy
(2020)

Neural Processes During Adolescent Risky Decision Making Are Associated with Conformity to Peer Influence

Adolescents often take more risks, especially with peers, which can be both harmful and beneficial. This study explores how brain activity and connections relate to risky driving under peer influence.

AdolescentsRisk takingPeer influenceDrivingfMRIBART
(2020)

Mechanisms Linking Childhood Trauma Exposure and Psychopathology: a Transdiagnostic Model of Risk and Resilience

Childhood trauma is a significant risk factor for various mental health conditions throughout life. It influences social, emotional, and biological development, increasing vulnerability to psychopathology.

StressTraumaAdolescentsMental health disordersEmotional controlAging
(2020)

"Permanently Incorrigible" Is a Patently Ineffective Standard: Reforming the Administration of Juvenile Life Without Parole

This article examines challenges in applying the Supreme Court's "irreparable corruption" standard for juvenile life without parole.

juvenile life without paroleJLWOPEighth amendmentMiller v. Alabamapermanent incorrigibilitydiscretionary JLWOP sentencemitigating factorsMontgomery v. LouisianaSixth Amendment
(2020)

Healthy Development as a Human Right: Insights from Developmental Neuroscience for Youth Justice

This article argues that healthy development is a human right, not a privilege. It highlights how the US justice system often denies this right to youth, especially children of color, by treating them as adults.

Brain developmentLawAdolescenceRightsBraincognitiondevelopment
(2020)

Estimating the impact of wide scale uptake of screening and medications for opioid use disorder in US prisons and jails

Implementing medication for opioid use disorder in all US prisons and jails could prevent many overdose deaths. An estimated 3,200 to 11,200 lives could be saved annually if these treatments were widely available.

jailmedications for opioid use disorderopioidsoverdoseprison
(2020)

Alcohol Addiction, Gut Microbiota, and Alcoholism Treatment: A Review

Alcohol use disorder causes significant death and disability, impacting brain function and increasing risks of anxiety, depression, and liver disease. Current treatments offer limited success, highlighting a need for new interventions.

CRISPRalcohol addictionalcohol encephalopathyalcohol liver diseasealcoholism medicationgene editing therapygut microbiotagut–brain axis
(2020)

E-cigarettes, nicotine, the lung and the brain: Multi-level cascading pathophysiology

E-cigarettes are perceived as safer than tobacco, but their health effects, especially on the brain and lungs, are not fully understood. Research is struggling to keep pace with increasing use and changing perceptions.

E-cigarettesnicotinelung diseaseaddictionsmoking cessationbrain
(2020)

Sex Differences in the Neurobiology of Alcohol Use Disorder

This article highlights that sex differences influence alcohol use disorder (AUD) risk. Researchers are increasingly including females in studies to understand how sex impacts the transition from alcohol use to misuse.

adolescencealcoholalcohol use disorderanimal modelsbrainsex differencesstressprefrontal cortexbinge drinkingalcohol withdrawal
(2020)

Insights into the neurobiology of craving in Opioid Use Disorder

Opioid Use Disorder (OUD) is driven by brain changes that enhance drug-related craving. This craving, a complex interplay of reward, stress, and learning, fuels drug-seeking and relapse.

Drug cravingIncentive sensitizationNegative affectNegative reinforcementOpioid Use DisorderStress
(2020)

Methamphetamine Use Disorder: The Next Addiction Crisis

Methamphetamine use and overdose deaths have significantly increased, posing a major public health challenge. The drug's complex neurobiology extends beyond traditional views, affecting multiple biological pathways in the brain.

Methamphetamine use disorderneurobiologytreatmentcognitive impairmentcardiovascular diseasepharmacological interventions
(2020)

Attention-deficit/hyperactivity disorder and lifetime cannabis use: Genetic overlap and causality

The study found a shared genetic basis between ADHD and lifetime cannabis use. This shared genetic background may partially explain why individuals with ADHD have a higher risk of cannabis use.

ADHDcannabis usegenetic correlationsubstance use disorderheritability
(2020)