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Efficacy of Cognitive Behavioral Therapy for alcohol and other drug use disorders: Is a one-size-fits-all approach appropriate?

Cognitive Behavioral Therapy (CBT) for alcohol and drug use disorders is a widely studied and used treatment. It helps individuals learn coping skills to change thoughts and behaviors related to substance use.

behavioral treatmentclinical trialsmechanisms of behavior changesubstance use disorder
(2023)

Updated perspectives on the neurobiology of substance use disorders using neuroimaging

Substance use disorders involve brain changes affecting decision-making and reward. Neuroimaging helps understand these alterations, which are influenced by genetics and other factors.

MRIneuroiologysubstance useaddictionneuroimagingAIPETfMRISPECT
(2023)

A comparison of medication-assisted treatment options for opioid addiction: A review of the literature

This literature review investigates medication-assisted treatments for opioid use disorder. It focuses on the efficacy of buprenorphine, methadone, and naltrexone in reducing relapse and harm.

buprenorphineharm reductionMATmedication-assisted treatmentmethadonenaltrexoneopioid addictionopioid use disorderreturn to use reduction
(2023)

Value-based decision-making network functional connectivity correlates with substance use and delay discounting behaviour among young adults

Research aims to find biological markers for substance use disorders. This involves using new dimensional models that combine categories and continuous measures to better understand who might be at risk.

Substance Use DisordersSusceptibility BiomarkersFunctional ConnectivityNeuroimagingFactor Mixture ModellingPreaddiction Delay Discounting Brain NetworksDimensional ModelsHuman Connectome Project
(2023)

Consumer Fraud against Older Adults in Digital Society- Examining Victimization and Its Impact

Population aging will lead to more older people experiencing financial exploitation. While older adults have traditionally been seen as vulnerable, their lower digital activity may offer some protection from online fraud.

older adultssenior citizensfraudconsumer fraudcyber fraudpopulation agingvulnerabilityfinancial impactnon-financial impactinternet use
(2023)

Circuit dysfunctions of associative and sensorimotor basal ganglia loops in alcohol use disorder: insights from animal models

Alcohol use disorder (AUD) is linked to brain circuit dysfunction that affects decision-making and action control. Understanding these changes, particularly in the basal ganglia, could help improve AUD therapies.

alcohol use disorderAction ControlBasal GangliaCircuitsSynapses
(2023)

In re Jayden M.

The court denied reunification services due to the mother's 20-year substance use history and failed treatment efforts. Her recent progress was insufficient, given the long-standing issues.

reunification servicesdependency lawsubstance usedrug treatmentparental rightschild welfarereasonable effortscase lawdependency courtfailed reunification
(2023)

Sager v. Duvert

The court ruled a man's lawsuit, claiming doctors negligently caused his opioid addiction through overprescribing, was filed too late under state law. Summary judgment for the doctors was upheld.

opioid addictionoverprescribingmedical malpracticesummary judgmentstatute of limitationsnegligent overprescriptionopioid lawsuitmedical negligencepharmaceutical litigation
(2023)

Sexton v. State

The court reversed a sentence reduction denial, finding the judge improperly deferred to the parole board. The judge should have weighed the defendant's youth, addiction, and rehabilitation.

sentence reductionJUVRAparole boardyouthaddictionrehabilitation
(2023)

Neural circuits controlling choice behavior in opioid addiction

Opioid use disorder is a growing epidemic characterized by choosing drugs over natural rewards. Research explores the brain's opioid system and neural circuits to develop new treatments that shift this choice behavior.

Opioid use disorderneural circuitschoice behaviordopamineprefrontal cortexvmPFCNAshellpharmacotherapiesreturn to use
(2023)

Chronic alcohol exposure differentially alters calcium activity of striatal cell populations during actions

Chronic alcohol exposure leads to lasting increases in direct pathway activity but reduces indirect pathway and PV interneuron activity in the brain's decision-making region. This imbalance may contribute to impaired behavioral control.

Dorsal medial striatumAlcoholDecision-makingDirect pathwayIndirect pathway
(2023)

Anticipatory reward dysfunction in alcohol dependence: An electroencephalography monetary incentive delay task study

This study investigated reward processing in alcohol-dependent individuals using EEG.

Event-related potentialsAlcohol dependenceRewardEEGAddictionComputational psychiatry
(2023)

Is Adolescence Believed to be a Period of Greater Risk Taking Than Adulthood?

Adolescents and adults both perceive adolescence as a period of higher risk-taking, especially due to peer presence. This study explores these beliefs using both explicit and implicit measures.

adolescencerisk takingbeliefspeer influenceadulthoodbelief bias
(2023)

Prescription psychostimulants for cocaine use disorder: A review from molecular basis to clinical approach

Cocaine use disorder lacks FDA-approved treatment options. Prescription psychostimulants, which share pharmacological effects with cocaine, show promise in promoting abstinence and reducing drug use.

Cocaine use disorderprescription psychostimulantsamphetaminemethylphenidatemodafinilagonist replacement therapydopamine transporterabstinenceharm reductiontreatment retention
(2023)

Project Harmony: A Meta-Analysis With Individual Patient Data on Behavioral and Pharmacologic Trials for Comorbid Posttraumatic Stress and Alcohol or Other Drug Use Disorders

New research analyzed 36 trials to find the most effective treatments for co-occurring PTSD and substance use disorders. It found various behavioral and pharmacotherapy options, but noted a need for more comparative studies.

Posttraumatic stress disorder (PTSD)substance use disordertrauma-focused therapyalcohol use disorderbehavioral treatmentmeta-analysiscomparative effectivenessintegrated treatment
(2023)