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Atypical effective connectivity from the frontal cortex to striatum in alcohol use disorder
This study investigates brain alterations in alcohol use disorder (AUD) using brain imaging. It finds specific brain regions contribute to classifying individuals with AUD from healthy controls.
Prefrontal electrophysiological biomarkers and mechanism-based drug effects in a rat model of alcohol addiction
Alcohol use disorder treatment outcomes vary, prompting a search for biomarkers. This study found that certain brain activity patterns, disturbed in individuals with AUD, could predict relapse risk and treatment success.
How should harm reduction be included in care continua for patients with Opioid Use Disorder?
Harm reduction practices aim to reduce negative consequences of substance use, but face barriers like stigma and policy objections. Physicians and policymakers should integrate harm reduction into services and adopt evidence-based policies.
Co-occurring trauma- and stressor-related and substance-related disorders in youth: A narrative review
Many European youth experience trauma and use substances. Trauma increases a young person's risk for substance use problems, including substance use disorder, and both are often underdiagnosed in youth.
Neuroanatomical Variability and Substance Use Initiation in Late Childhood and Early Adolescence
Brain structure differences may be both a cause and consequence of substance use. Smaller global neuroanatomical indices are linked to substance use initiation, even before use begins.
Neurobiology, psychotherapeutic interventions, and emerging therapies in addiction: a systematic review
Addiction involves brain changes affecting reward and control. Therapies like CBT, EMDR, and psychedelics, as well as neurostimulation, can help repair these neural pathways.
The Brain Salience Network at the Intersection of Pain and Substance use Disorders: Insights from Functional Neuroimaging Research
Individuals with substance use disorders exhibit brain changes in their salience network, which handles pain and attention. These alterations are linked to cognitive and behavioral problems.
The end of “permanently incorrigible”: Putting Jones v. Mississippi into context
This article supports the Supreme Court’s decision in Jones v. Mississippi but argues for eliminating life without parole sentences for all juveniles.
What Goes Up but Never Comes Down? Juvenile Punitive Practice Within the United States
The U.S. juvenile justice system is punitive and lacks a uniform federal approach, unlike many nations that follow international standards. This leads to higher re-incarceration rates and fails to adequately protect incarcerated youth.
Shrinking the Footprint of the Criminal Legal System Through Policies Informed by Psychology and Neuroscience
Psychology and neuroscience can improve the legal system by shaping policies. Findings show that prison conditions, like pollution and solitary confinement, negatively impact health and could be reformed with scientific insight.
Amending New Jersey’s Expungement Law to Reflect the Historical Treatment of Juveniles: Juveniles Deserve a Second Chance
The article finds that New Jersey's law prevents expunging certain juvenile offenses, regardless of rehabilitation. This forces many to seek less effective record sealing, which still allows some disclosure of past acts.
Structural brain changes associated with cocaine use and digital cognitive behavioral therapy in cocaine use disorder treatment
This study investigates how digital cognitive behavioral therapy (CBT4CBT) and galantamine affect brain structure in individuals with cocaine use disorder. Researchers examined changes in gray matter volume over 12 weeks of treatment.
PrEP facilitators and barriers in substance use bridge clinics for women who engage in sex work and who use drugs
Women who use drugs and engage in sex work face disproportionately high HIV risks, yet PrEP uptake among this group remains very low. Bridge clinics offer a key opportunity to increase PrEP access.
Degradation or Redemption? A Parole Board Polices a Moral Boundary
A parole board denied release to a woman convicted as a juvenile, despite a low risk of re-offending. An appeals court mandated her release, highlighting how moral factors can improperly influence parole decisions.
Cannabis cue-reactivity in cannabis use disorder: Diverging evidence in tow distinct cannabis cultures
Cannabis decriminalization affects public attitudes and perceived harm, influencing use and addiction risk. This study explores how differing cannabis policies in Texas and Amsterdam relate to attitudes and brain responses to cannabis cues.