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The effects of naltrexone on retention in treatment and being opioid-free in opioid-dependent people: A systematic review and meta-analysis

A review found naltrexone treatment for opioid dependence increased patients staying in treatment and remaining opioid-free. It highlights the drug's effectiveness for recovery.

opioidnaltrexoneretention in treatmentopioid freesystematic reviewmeta-analysis
(2022)

FOXN3 and GDNF Polymorphisms as Common Genetic Factors of Substance Use and Addictive Behaviors

Addictions to substances and behaviors share psychological, biological, and genetic overlaps. These conditions often co-occur and involve similar brain systems and genetic predispositions.

addictive behaviorsgenetic association analysissubstance usesubstance-related disordersFOXN3GDNF
(2022)

Meeting people where they are: Implementing hospital-based substance use harm reduction

A hospital implemented harm reduction education and supplies for patients with substance use disorder. This intervention aimed to integrate evidence-based care and reduce stigma.

Harm reductionsubstance use disorderoverdosesyringe service programsaddiction treatmenthospital-based carenaloxonefentanyl test stripssafer use suppliesstigma
(2022)

The Use of Chatbots as Supportive Agents for People Seeking Help with Substance Use Disorder: A Systematic Review

Technology has expanded social support for health, notably during the pandemic, with chatbots emerging as a popular, non-judgmental, and accessible tool for various health needs, including addiction recovery.

ChatbotAlcoholDrugsSubstanceSubstance use disorderAddictionSystematic review
(2022)

The intersection of empathy and addiction

This article explores the connection between empathy and Substance Use Disorder (SUD). It finds that individuals with SUD often show diminished empathy, and this may be both a consequence and a precursor to the disorder.

Empathyaddictionsubstance use disorderprosocial behaviorrodent models
(2022)

“It’s probably going to save my life:” Attitudes towards treatment among people incarcerated in the era of Fentanyl

The opioid crisis has led to a significant increase in overdose deaths, largely due to fentanyl. People in the criminal legal system are disproportionately affected, prompting programs like Rhode Island's MOUD to reduce fatalities.

fentanylopioid use disordermedication for opioid use disorderincarcerationharm reduction
(2022)

The Mexican magnetic resonance imaging dataset of patients with cocaine use disorder: SUDMEX CONN

This study investigates cocaine use disorder by comparing brain structure and function in people with the disorder and healthy controls. Researchers used MRI scans and cognitive tests to understand how cocaine affects the brain.

Cocaine use disorderMRIneuroimagingsubstance use disorderbrain structurefunctional connectivityresting-state fMRIdiffusion MRIcognitive functionSUDMEX CONN
(2022)

Network Analysis of DSM Symptoms of Substance Use Disorders and Frequently Co-Occurring Mental Disorders in Patients with Substance Use Disorder Who Seek Treatment

Substance use disorders often co-occur with other mental health conditions. Understanding the links between symptoms across these disorders can improve diagnosis and treatment outcomes.

network analysissubstance use disordersADHDcomorbiditypersonality disordersgender differencesborderline personalityconduct disorder
(2022)

Opioid Overdose Deaths Among Formerly Incarcerated Persons and the General Population: North Carolina, 2000‒2018

Formerly incarcerated persons in North Carolina face a significantly higher risk of opioid overdose death compared to the general population, especially from synthetic narcotics like fentanyl. This risk is highest immediately after release.

Formerly incarcerated persons opioid overdose deathNorth Carolinapostreleasefentanylstandardized mortality ratiosubstance use disordersre-entryopioid epidemicincarceration
(2022)

The prevalence of comorbid serious mental illnesses and substance use disorders in prison populations: a systematic review and meta-analysis

Many people in prison have co-occurring serious mental illnesses and substance use disorders. This significantly increases their risk of reincarceration and suicide attempts after release.

Prison populationdual disorderscomorbid mental illnesssubstance use disorderspsychosismajor depressionincarcerationtreatment outcomesintegrated servicesmental health in prison
(2022)

Defining Recovery From Alcohol Use Disorder: Development of an NIAAA Research Definition

The article introduces a new research definition of recovery from Alcohol Use Disorder (AUD) developed by NIAAA. This definition aims to standardize research, track the course of AUD, and improve understanding of treatment responses.

Alcohol use disorderrecoveryDSM-5 AUDNIAAA definitionheavy drinkingremissionabstinencebiopsychosocial functioningwell-beingtreatment
(2022)

Novel Agents for the Pharmacological Treatment of Alcohol Use Disorder

Alcohol use disorder is often undertreated. New and existing medications show promise for future treatment, including personalized approaches for diverse patient needs.

Alcohol use disordertreatmentpharmacotherapiesnaltrexoneacamprosatedisulfiramharm reductionabstinencerepurposed medicationsnovel agents
(2022)

Gene-based polygenic risk scores analysis of Alcohol Use Disorder in African Americans

This study proposes a new gene-based method to improve genetic risk prediction for alcohol use disorder in diverse populations. It focuses on shared disease-causing genes between different ancestries.

Alcohol use disorderpolygenic risk scoregenome-wide association studyAUD risk predictiondrug targets
(2022)

Alcohol Use Disorder in the COVID-19 era: Position paper of the Italian Society on Alcohol (SIA)

The Italian Society of Alcohology (ISA) developed guidelines for managing alcohol use disorder (AUD) in COVID-19 patients. This addresses increased AUD during lockdowns and the unique challenges posed by co-occurring COVID-19 infection.

COVID-19alcohol use disordertelehealthtelemedicinedrug interactionsalcohol consumptionliver cirrhosisrelapse preventionCAATsvaccination
(2022)

Understanding Stimulant Use and Use Disorders in a New Era

Drug overdose deaths are rising due to illicit opioids, stimulants like methamphetamine and cocaine, and their co-use. This "fourth wave" of mortality is driven by increased supply and potency of these substances.

Behavioral treatmentsCocaineEpidemiologyFentanylMedication treatmentsMethamphetamineNeurobiologyPharmacology
(2022)
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