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Racial disparities in linkage to care among patients with substance use disorders

Peer support specialists may help link people with substance use disorders to treatment. However, Black patients were less likely to engage in treatment through these specialists in the emergency department.

Peer support specialistsSubstance useRacial disparitiesDiversity and inclusionOpioid use disorderAlcohol use disorderSubstance use disorderAddiction treatmentPublic health
(2022)

Current status of vaccines for substance use disorders: A brief review of human studies

Vaccines for substance use disorders face significant hurdles for human use. While some drug vaccines show promise in animal studies, none have successfully promoted abstinence or reduced drug use in humans.

VaccineAnti-addictionOpiatesNicotineStimulants
(2022)

Longitudinal Analysis of Substance Use Disorder Symptom Severity at Age 18 Years and Substance Use Disorder in Adulthood

Adolescent substance use disorder symptoms are linked to prescription drug use and misuse in adulthood. Those with more severe symptoms as teens face a higher risk of substance use issues later in life.

Substance use disorderadolescenceprescription drug useopioid crisispolysubstance uselongitudinal studyscreening
(2022)

Neural Underpinnings of Social Stress in Substance Use Disorders

Individuals with substance use disorders often use drugs to cope with emotional pain, particularly from chronic social stress. This stress can affect brain responses to drugs and worsen illness risk.

Human drug addictionNeuroimagingSocial stressSubstance use disorderEarly and lifetime adversitytraumareward systembrain connectivityfMRIstress hormones
(2022)

The addiction risk factor: A unitary genetic vulnerability characterizes substance use disorders and their associations with common correlates

Substance use disorders and other mental health conditions share common genetic vulnerabilities. Understanding these genetic links could lead to better prevention and treatment.

Genetics researchBehavioural geneticsAddictionSubstance use disordergenetic liabilitypsychopathologyrisk-takingexecutive functionneuroticismgenome-wide association study (GWAS)genetic correlationpolygenic liability
(2022)

Neuropsychiatric Model of Addiction Simplified

Research shows addiction is a chronic, relapsing brain disorder influenced by both genetics and environment. Early life stress increases substance use risk, but interventions can mitigate these effects.

AddictionAddiction cycleNeurobiologyReinforcementdopaminewithdrawalrelapseneuroplasticitycravingtreatment
(2022)

The effects of naltrexone on retention in treatment and being opioid-free in opioid-dependent people: A systematic review and meta-analysis

A review found naltrexone treatment for opioid dependence increased patients staying in treatment and remaining opioid-free. It highlights the drug's effectiveness for recovery.

opioidnaltrexoneretention in treatmentopioid freesystematic reviewmeta-analysis
(2022)

FOXN3 and GDNF Polymorphisms as Common Genetic Factors of Substance Use and Addictive Behaviors

Addictions to substances and behaviors share psychological, biological, and genetic overlaps. These conditions often co-occur and involve similar brain systems and genetic predispositions.

addictive behaviorsgenetic association analysissubstance usesubstance-related disordersFOXN3GDNF
(2022)

Meeting people where they are: Implementing hospital-based substance use harm reduction

A hospital implemented harm reduction education and supplies for patients with substance use disorder. This intervention aimed to integrate evidence-based care and reduce stigma.

Harm reductionsubstance use disorderoverdosesyringe service programsaddiction treatmenthospital-based carenaloxonefentanyl test stripssafer use suppliesstigma
(2022)

The Use of Chatbots as Supportive Agents for People Seeking Help with Substance Use Disorder: A Systematic Review

Technology has expanded social support for health, notably during the pandemic, with chatbots emerging as a popular, non-judgmental, and accessible tool for various health needs, including addiction recovery.

ChatbotAlcoholDrugsSubstanceSubstance use disorderAddictionSystematic review
(2022)

The intersection of empathy and addiction

This article explores the connection between empathy and Substance Use Disorder (SUD). It finds that individuals with SUD often show diminished empathy, and this may be both a consequence and a precursor to the disorder.

Empathyaddictionsubstance use disorderprosocial behaviorrodent models
(2022)

“It’s probably going to save my life:” Attitudes towards treatment among people incarcerated in the era of Fentanyl

The opioid crisis has led to a significant increase in overdose deaths, largely due to fentanyl. People in the criminal legal system are disproportionately affected, prompting programs like Rhode Island's MOUD to reduce fatalities.

fentanylopioid use disordermedication for opioid use disorderincarcerationharm reduction
(2022)

The Mexican magnetic resonance imaging dataset of patients with cocaine use disorder: SUDMEX CONN

This study investigates cocaine use disorder by comparing brain structure and function in people with the disorder and healthy controls. Researchers used MRI scans and cognitive tests to understand how cocaine affects the brain.

Cocaine use disorderMRIneuroimagingsubstance use disorderbrain structurefunctional connectivityresting-state fMRIdiffusion MRIcognitive functionSUDMEX CONN
(2022)

Network Analysis of DSM Symptoms of Substance Use Disorders and Frequently Co-Occurring Mental Disorders in Patients with Substance Use Disorder Who Seek Treatment

Substance use disorders often co-occur with other mental health conditions. Understanding the links between symptoms across these disorders can improve diagnosis and treatment outcomes.

network analysissubstance use disordersADHDcomorbiditypersonality disordersgender differencesborderline personalityconduct disorder
(2022)

Opioid Overdose Deaths Among Formerly Incarcerated Persons and the General Population: North Carolina, 2000‒2018

Formerly incarcerated persons in North Carolina face a significantly higher risk of opioid overdose death compared to the general population, especially from synthetic narcotics like fentanyl. This risk is highest immediately after release.

Formerly incarcerated persons opioid overdose deathNorth Carolinapostreleasefentanylstandardized mortality ratiosubstance use disordersre-entryopioid epidemicincarceration
(2022)
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