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United States v. Adair

The court upheld Adair's 168-month sentence for leading an opioid ring. Despite her own addiction, she directed others and played a key organizing role in the operation.

opioid ringdrug traffickingsentencingorganized crimeaddiction
(2022)

State v. Casper

The Idaho Supreme Court upheld Casper's sentence and restitution. His extensive meth use, failed treatments, and violent history justified incarceration over rehabilitation.

sentencerestitutionmethdrug userehabilitationincarceration violent behaviortreatment
(2022)

United States v. Jocelyn Lopez-Sanchez

The court denied early release for Jocelyn Lopez-Sanchez, serving a fentanyl sentence. Her history of substance use and mental illness was not deemed "extraordinary" enough for compassionate release.

Compassionate releasefentanyl sentenceearly release substance usemental illness12-year sentencedenied release
(2022)

United States v. Horace Johnson

The court denied compassionate release due to Johnson's COVID-19 vaccine refusal, prior infection, and low prison case rates, despite his obesity and opioid use disorder.

compassionate releaseobesityopioid use disordervaccine refusaldenied releasecompelling risk
(2022)

The neurobiology of drug addiction: Cross-species insights into the dysfunction and recovery of the prefrontal cortex

Drug addiction is a chronic disease that causes widespread brain changes. This article reviews how drug abuse affects the prefrontal cortex, which is involved in emotion and decision-making.

Drug addictionprefrontal cortexiRISA modelinhibitory controlattention biasreward-related decision-makinginsight into illnessgray matterwhite matterneuroimaging
(2022)

Association of drug cues and craving with drug use and relapse: A systematic review and meta-analysis

A review of 237 studies found a significant link between drug cues, craving, and future drug use or relapse. These findings suggest that drug cues and craving are key factors in understanding drug use.

drug cuescravingdrug userelapsesubstance use disorders (SUDs)cue reactivitycue-induced cravingmeta-analysissystematic reviewdrug relapse
(2022)

Prevalence of Mental Health Needs, Substance Use, and Co-occurring Disorders Among People Admitted to Prison

The number of people admitted to prison with both mental health needs and substance use disorders rose between 2009 and 2017. Methamphetamine and heroin use disorders increased, while cocaine use disorder decreased.

Co-occurring disorders mental health needssubstance use disordersprison populationmethamphetamine use disorderheroin use disordercocaine use disorderincarcerationJail Screening Assessment Tool (JSAT)integrated treatment
(2022)

Gender differences among persons entering medication treatment for opioid use disorder in the community

Women beginning medication treatment for opioid use disorder (MOUD) were younger, more often White non-Hispanic and LGBTQ+, and had less incarceration than men.

Opioid use disorderMOUDwomengender differencesmental healthPTSDsubstance use disorderquality of lifeco-occurring disordersharm reduction
(2022)

Factors associated with retention on medications for opioid use disorder among a cohort of adults seeking treatment in the community

People with opioid use disorder who initiated methadone or buprenorphine treatment in the community experienced better retention when they had stable housing and were not using cocaine. Individuals referred from jail had lower retention.

Opioid use disorderMedication-assisted treatmentMOUD retentionMethadoneBuprenorphineHousing statusPain interferenceHIVCocaine useHigh dose MOUD
(2022)

Racial disparities in linkage to care among patients with substance use disorders

Peer support specialists may help link people with substance use disorders to treatment. However, Black patients were less likely to engage in treatment through these specialists in the emergency department.

Peer support specialistsSubstance useRacial disparitiesDiversity and inclusionOpioid use disorderAlcohol use disorderSubstance use disorderAddiction treatmentPublic health
(2022)

Current status of vaccines for substance use disorders: A brief review of human studies

Vaccines for substance use disorders face significant hurdles for human use. While some drug vaccines show promise in animal studies, none have successfully promoted abstinence or reduced drug use in humans.

VaccineAnti-addictionOpiatesNicotineStimulants
(2022)

Longitudinal Analysis of Substance Use Disorder Symptom Severity at Age 18 Years and Substance Use Disorder in Adulthood

Adolescent substance use disorder symptoms are linked to prescription drug use and misuse in adulthood. Those with more severe symptoms as teens face a higher risk of substance use issues later in life.

Substance use disorderadolescenceprescription drug useopioid crisispolysubstance uselongitudinal studyscreening
(2022)

Neural Underpinnings of Social Stress in Substance Use Disorders

Individuals with substance use disorders often use drugs to cope with emotional pain, particularly from chronic social stress. This stress can affect brain responses to drugs and worsen illness risk.

Human drug addictionNeuroimagingSocial stressSubstance use disorderEarly and lifetime adversitytraumareward systembrain connectivityfMRIstress hormones
(2022)

The addiction risk factor: A unitary genetic vulnerability characterizes substance use disorders and their associations with common correlates

Substance use disorders and other mental health conditions share common genetic vulnerabilities. Understanding these genetic links could lead to better prevention and treatment.

Genetics researchBehavioural geneticsAddictionSubstance use disordergenetic liabilitypsychopathologyrisk-takingexecutive functionneuroticismgenome-wide association study (GWAS)genetic correlationpolygenic liability
(2022)

Neuropsychiatric Model of Addiction Simplified

Research shows addiction is a chronic, relapsing brain disorder influenced by both genetics and environment. Early life stress increases substance use risk, but interventions can mitigate these effects.

AddictionAddiction cycleNeurobiologyReinforcementdopaminewithdrawalrelapseneuroplasticitycravingtreatment
(2022)
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