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Sex/Gender Differences in the Time-Course for the Development of Substance Use Disorder: A Focus on the Telescoping Effect

Women often experience a faster progression from initial substance use to developing a substance use disorder, known as the "telescoping effect." This pattern is seen with various substances, though some recent studies show inconsistencies.

telescoping effectsubstance use disorderwomenaddictionovarian hormonessex differencesdopamineglutamatemesolimbic pathway
(2023)

Neuroimaging in Adolescents: Post-Traumatic Stress Disorder and Risk for Substance Use Disorders

Adolescents with PTSD have brain changes that may link to developing substance use disorders (SUDs). This review examines neuroimaging studies on this connection and discusses prevention and accurate diagnosis.

adolescenceSUDsPTSDepigeneticsmemoryneuroimagingSUDSubstance Use DisorderLimbic SystemTraumaEpigenetics
(2023)

Neural mechanisms linked to treatment outcomes and recovery in substance-related and addictive disorders

This article reviews brain-based factors tied to recovery from substance use and behavioral addictions. It explores how various treatments, including medication and therapy, relate to brain mechanisms and improved outcomes.

Neurobiologyrecoverysubstance-related disordersgambling disorderinternet gaming disorderimpulsivityaddictive behavioursinternet addictionrecovery processespharmacological treatmentscognitive behavioral therapytreatment outcomes
(2023)

Three decades of research in substance use disorder treatment for syringe services program participants: A scoping review of the literature

Syringe Services Programs reduce disease transmission and connect people who use drugs to medical care. These programs are potential sites to expand substance use disorder treatment, including medication for opioid use disorder.

syringe services programreferral to treatmentpeople who inject drugs
(2023)

Motivated to Compete but Not to Care: The Fundamental Social Motives of Risk-Taking Behaviors

Risk-taking behaviors in adolescents and young adults are often linked to gaining social status and finding mates. These behaviors are more prevalent in young males, aligning with evolutionary drives for reproductive success.

risk-takingteensyoung adultssocial pressurekin caresocial motives
(2023)

Polygenic Risk Scores and Brain Structures Both Contribute to Externalizing Behavior in Childhood: A Study in the Adolescent Brain and Cognitive Development (ABCD) Cohort

Genetic risk for externalizing behaviors in children is associated with differences in brain structure. These brain structures may influence how genetic risks contribute to behavioral issues.

Externalizing behaviorsLate childhoodAdolescenceGray matter volumeWhite matter integrityPolygenic risk scoresMagnetic resonance imagingMRI
(2023)

Put the Juvenile Back in Juvenile Court

Many states determine juvenile court jurisdiction by an offender's age at the time of legal proceedings, not the offense.

rehabilitationjuvenile justiceage of majority
(2023)

Reappraising the Role of Dopamine in Adolescent Risk-Taking Behavior

Dopamine in the brain plays a key role in motivation and reward. Changes in dopamine pathways during adolescence are linked to increased sensation-seeking and risk-taking behaviors.

adolescencedopamineself-regulationimpulsivityrisk-taking
(2023)

Risk Decision Making and Executive Function Among Adolescents and Young Adults

Adolescence involves increased risky behaviors. Research suggests differences in risk decision-making between young adults and adolescents are linked to improvements in executive function.

Decision-makingbrain developmentteenagersadolescenceyoung adultsrisk-takingexperimentdual system modelexecutive functiondecision-makingIowa Gambling Taskrisk
(2023)

Estimated Costs and Outcomes Associated with Use and Nonuse of Medications for Opioid Use Disorder During Incarceration and at Release in Massachusetts

Treating incarcerated individuals with opioid use disorder (OUD) through screening and medication can save lives and reduce healthcare costs. This approach also improves treatment retention after release.

Opioid Use DisorderMedications for Opioid Use DisorderMethadoneBuprenorphineNaltrexoneOverdose mortalityIncarcerationCost-effectivenessRESPOND model
(2023)

The role of substance use treatment in reducing stigma after release from incarceration: A qualitative analysis

Substance use treatment may reduce the stigma experienced by individuals recently released from incarceration. Positive interactions with treatment staff and peers could lessen feelings of shame and judgment.

Substance use disordersincarcerationstigmasubstance use treatmentreentryrecidivismself-stigmaperceived stigmarecoverytreatment engagement
(2023)

Racial inequities and addiction research

NIDA prioritizes research on health disparities and diversity in the scientific workforce, studying substance use trends and underlying causes. Acknowledging race and ethnicity data limitations is key to developing effective interventions.

Racial equityDisparitiesAddiction research
(2023)

The role of substance use in the lives of incarcerated older adults: A qualitative study

The number of incarcerated older adults (IOAs) and their drug abuse has risen. Research on IOAs and drug abuse is limited, despite this group's unique drug use patterns and a surprising lack of treatment programs.

Incarcerated older adultsdrug abuseaginglife-course perspectivesubstance use disorderprisonqualitative researchphenomenological analysisdrug use trajectoriestransitionsturning points
(2023)

“Safer Drug Supply” Measures in Canada to Reduce the Drug Overdose Fatality Toll: Clarifying Concepts, Practices and Evidence Within a Public Health Intervention Framework

Canada and the US face a drug toxicity crisis, primarily from synthetic opioids. Current interventions have not stopped rising deaths. "Safer supply" initiatives aim to reduce overdose risk by providing pharmaceutical-grade drugs.

Opioid overdosesafer supplydrug death crisisillicit opioidsfentanylharm reductionoverdose preventionaddiction treatmentdiversion
(2023)

Treating addiction with deep brain stimulation: Ethical and legal considerations

Early brain surgeries for mental health problems led to serious side effects. Newer brain stimulation methods are being explored for addiction, showing some promise but needing more research.

AddictionBioethicsDeep brain stimulationNeuromodulationNeuropsychiatrySubstance uselegal implicationsinformed consent
(2023)